Evidence map›Paper›PMID 18931855›Full record

ArticleLangenbeck's archives of surgery2009

Microscopic cancer cell spread in gastric cancer: whole-section analysis of mesogastrium.

Atsuko Nagatomo, Nobutsugu Abe, Hirohisa Takeuchi, Osamu Yanagida, Tadahiko Masaki, Toshiyuki Mori, Masanori Sugiyama, Yasuo Ohkura, Yasunori Fujioka, Yutaka Atomi

Registry-linked trialAbstract read
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In one paragraph

Article in Langenbeck's archives of surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01978444 (Prospective Randomized Controlled Trial of Laparoscopic D2 Lymphadenectomy Plus Complete Mesogastrium Excision(D2+CME)vs. Laparoscopic D2 Lymphadenectomy for Advanced Gastric Cancer), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01978444 naunknown statusnot on this mapstarted 2014, after this paper: background citation

Prospective Randomized Controlled Trial of Laparoscopic D2 Lymphadenectomy Plus Complete Mesogastrium Excision(D2+CME)vs. Laparoscopic D2 Lymphadenectomy for Advanced Gastric Cancer

TypeinterventionalSponsorHuazhong University of Science and TechnologyRan2014 to 2023Enrolled169ConditionsGastric CancerArmsLaparoscopic D2 lymphadenectomy plus CME, Laparoscopic D2 lymphadenectomy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Atsuko NagatomoDepartment of Surgery, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka City, Tokyo, 181-8611, Japan. myuutarou30@ybb.ne.jp
Nobutsugu Abe
Hirohisa Takeuchi
Osamu Yanagida
Tadahiko Masaki
Toshiyuki Mori
Masanori Sugiyama
Yasuo Ohkura
Yasunori Fujioka
Yutaka Atomi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCancer cells are often found in adipose connective tissue separate from the primary lesion and outside lymph nodes on routine pathologic examination of resected gastric cancer specimens. To identify the anatomical relationship between such cancer cell spread and lymph nodes, we investigated the microscopic cancer cell spread in the mesogastrium (CSM) by the whole-section analysis of the mesogastrium.

methodOne thousand five hundred fifty-two sections of the mesogastrium obtained from 37 patients with gastric cancer were subjected. CSM is defined as the existence of cancer cell spread in the mesogastrium separate from the primary lesion.

resultsCSM was detected in three (8%) of the 37 patients. CSM was classified into three types. CSM was found in three of the 12 patients with advanced cancer, but not in 25 patients with early cancer.

conclusionsCSM may occur in the mesogastrium separate from metastatic lymph nodes; therefore, we should pay particular attention to the potential existence of CSM in surgery for gastric cancer.

Indexed as

AdenocarcinomaAdenocarcinoma, PapillaryAdultAgedFemaleHumansImmunohistochemistryLymphatic MetastasisMaleMesenteryMiddle AgedPrognosisStomach Neoplasms

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.