Trial reportJournal of acquired immune deficiency syndromes (1999)2008
Project Accept (HPTN 043): a community-based intervention to reduce HIV incidence in populations at risk for HIV in sub-Saharan Africa and Thailand.
Trial report in Journal of acquired immune deficiency syndromes (1999), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07064928 (We Are Together), which is not on this map. Cited by 92 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
We Are Together (WAT): Development and Testing of an Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Who cites it
92 citing papers in PubMed, 8 syntheses or guidelines pooled it, 151 citations in OpenAlex.
- A Systematic Review of HIV Testing Implementation Strategies in Sub-Saharan African Countries.AIDS and behavior · 2022Pooled it
- A Systematic Review of Interventions that Promote Frequent HIV Testing.AIDS and behavior · 2019Pooled it
- Implementation science and stigma reduction interventions in low- and middle-income countries: a systematic review.BMC medicine · 2019Pooled it
- Barriers and facilitators to implementation of cancer treatment and palliative care strategies in low- and middle-income countries: systematic review.International journal of public health · 2018Pooled it
- Mobile clinics for women's and children's health.The Cochrane database of systematic reviews · 2016Pooled it
- Which Psychological Factors are Related to HIV Testing? A Quantitative Systematic Review of Global Studies.AIDS and behavior · 2016Pooled it
- The impact of community mobilisation on HIV prevention in middle and low income countries: a systematic review and critique.AIDS and behavior · 2014Pooled it
- A systematic review of interventions to reduce HIV-related stigma and discrimination from 2002 to 2013: how far have we come?Journal of the International AIDS Society · 2013Pooled it
- Trial
- Effect of community-based voluntary counselling and testing on HIV incidence and social and behavioural outcomes (NIMH Project Accept; HPTN 043): a cluster-randomised trial.The Lancet. Global health · 2014Trial
- Trial
- NIMH Project Accept (HPTN 043): results from in-depth interviews with a longitudinal cohort of community members.PloS one · 2014Trial
- Mobile VCT: reaching men and young people in urban and rural South African pilot studies (NIMH Project Accept, HPTN 043).AIDS and behavior · 2013Trial
- A randomized trial to optimize HIV/TB care in South Africa: design of the Sizanani trial.BMC infectious diseases · 2013Trial
- Trial
- NIMH Project Accept (HPTN 043) HIV/AIDS community mobilization (CM) to promote mobile HIV voluntary counseling and testing (MVCT) in rural communities in Northern Thailand: modifications by experience.AIDS and behavior · 2012Trial
- No "magic bullet": exploring community mobilization strategies used in a multi-site community based randomized controlled trial: Project Accept (HPTN 043).AIDS and behavior · 2012Trial
- Health diplomacy and the adaptation of global health interventions to local needs in sub-Saharan Africa and Thailand: evaluating findings from Project Accept (HPTN 043).BMC public health · 2012Trial
- Trial
- HIV surveillance in a large, community-based study: results from the pilot study of Project Accept (HIV Prevention Trials Network 043).BMC infectious diseases · 2011Trial
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 9 institutions in 5 countries.
Funding
Abstract
backgroundChanging community norms to increase awareness of HIV status and reduce HIV-related stigma has the potential to reduce the incidence of HIV-1 infection in the developing world.
methodsWe developed and implemented a multilevel intervention providing community-based HIV mobile voluntary counseling and testing, community mobilization, and posttest support services. Forty-eight communities in Tanzania, Zimbabwe, South Africa, and Thailand were randomized to receive the intervention or clinic-based standard voluntary counseling and testing (VCT), the comparison condition. We monitored utilization of community-based HIV mobile voluntary counseling and testing and clinic-based standard VCT by community of residence at 3 sites, which was used to assess differential uptake. We also developed quality assurance procedures to evaluate staff fidelity to the intervention.
findingsIn the first year of the study, a 4-fold increase in testing was observed in the intervention versus comparison communities. We also found an overall 95% adherence to intervention components. Study outcomes, including prevalence of recent HIV infection and community-level HIV stigma, will be assessed after 3 years of intervention.
conclusionsThe provision of mobile services, combined with appropriate support activities, may have significant effects on utilization of voluntary counseling and testing. These findings also provide early support for community mobilization as a strategy for increasing testing rates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.