ArticleBiophysical journal2009
Raman study of mechanically induced oxygenation state transition of red blood cells using optical tweezers.
Article in Biophysical journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Raman Spectroscopy of Cell-Free Cervicovaginal Lavage for HPV Lesion Diagnosis: A Pilot Study.International journal of molecular sciences · 2025Article
- Comparison of the human's and camel's red blood cell deformability by optical tweezers and Raman spectroscopy.Biochemistry and biophysics reports · 2023Article
- The effects of lithium on human red blood cells studied using optical spectroscopy and laser trap.European biophysics journal : EBJ · 2023Article
- The effects of short term hyperglycemia on human red blood cells studied using Raman spectroscopy and optical trap.European biophysics journal : EBJ · 2021Article
- Review
- Diagnosing sickle cell disease and iron deficiency anemia in human blood by Raman spectroscopy.Lasers in medical science · 2020Article
- Atomic force microscopy and Raman spectra profile of blood components associated with exposure to cigarette smoking.RSC advances · 2020Article
- Micro-Raman Spectroscopy Analysis of Optically Trapped Erythrocytes in Jaundice.Frontiers in physiology · 2020Article
- Enhancing Double-Beam Laser Tweezers Raman Spectroscopy (LTRS) for the Photochemical Study of Individual Airborne Microdroplets.Molecules (Basel, Switzerland) · 2019Article
- Laser Raman tweezer spectroscopy to explore the bisphenol A-induced changes in human erythrocytes.RSC advances · 2019Article
- Normal saline-induced deoxygenation of red blood cells probed by optical tweezers combined with the micro-Raman technique.RSC advances · 2019Article
- Quantitative phase microscopy of red blood cells during planar trapping and propulsion.Lab on a chip · 2018Article
- Optimal occlusion uniformly partitions red blood cells fluxes within a microvascular network.PLoS computational biology · 2017Article
- Influence of Standard Laboratory Procedures on Measures of Erythrocyte Damage.Frontiers in physiology · 2017Article
- Model System Study of Environmentally Persistent Free Radicals Formation in a Semiconducting Polymer Modified Copper Clay System at Ambient Temperature.RSC advances · 2016Article
- Raman Spectroscopy of Optically Trapped Single Biological Micro-Particles.Sensors (Basel, Switzerland) · 2015Review
- Article
- Mechanochemistry of single red blood cells monitored using Raman tweezers.Biomedical optics express · 2012Article
- Micro-Raman spectroscopy of silver nanoparticle induced stress on optically-trapped stem cells.PloS one · 2012Article
- Effect of the size and shape of a red blood cell on elastic light scattering properties at the single-cell level.Biomedical optics express · 2011Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Raman spectroscopy was used to monitor changes in the oxygenation state of human red blood cells while they were placed under mechanical stress with the use of optical tweezers. The applied force is intended to simulate the stretching and compression that cells experience as they pass through vessels and smaller capillaries. In this work, spectroscopic evidence of a transition between the oxygenation and deoxygenation states, which is induced by stretching the cell with optical tweezers, is presented. The transition is due to enhanced hemoglobin-membrane and hemoglobin neighbor-neighbor interactions, and the latter was further studied by modeling the electrostatic binding of two of the protein structures.
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