Evidence map›Paper›PMID 18930352›Full record

Trial reportPain2008

Efficacy of percutaneous electrical nerve stimulation and therapeutic exercise for older adults with chronic low back pain: a randomized controlled trial.

Debra K Weiner, Subashan Perera, Thomas E Rudy, Ronald M Glick, Sonali Shenoy, Anthony Delitto

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pain, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 7 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 7 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effectiveness of pharmacological and non-pharmacological therapy on pain intensity and disability in older people with chronic nonspecific low back pain: a systematic review with meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Pooled it
  4. Pooled it
  5. Exercise therapy for chronic low back pain.The Cochrane database of systematic reviews · 2021
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pharmacological management of chronic low back pain in older patients: a randomized controlled trial of the effect of pregabalin and opioid administration.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2015
    Trial
  9. Trial
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Fear avoidance beliefs predict disability in older adults with chronic low back pain.PM & R : the journal of injury, function, and rehabilitation · 2012
    Article
  19. The role of chiropractic care in older adults.Chiropractic & manual therapies · 2012
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Debra K WeinerDepartment of Medicine, University of Pittsburgh, PA, USA Department of Anesthesiology, University of Pittsburgh, PA, USA Department of Psychiatry, University of Pittsburgh, PA, USA Department of Biostatistics, University of Pittsburgh, PA, USA Center for Integrative Medicine, University of Pittsburgh, PA, USA Department of Physical Therapy, University of Pittsburgh, PA, USA Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Subashan Perera
Thomas E Rudy
Ronald M Glick
Sonali Shenoy
Anthony Delitto
University of Pittsburgh · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Functional Impact of PENS for 65+ Chronic Low Back PainR01AT000985 · NCCIH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WEINER, DEBRA KAYE · 2003 to 2006
$1.4M
NCCIH NIH HHS R01 AT000985NIA NIH HHS P30 AG-024827NIA NIH HHS P30 AG024827
6 · The paper itself

Abstract

Chronic low back pain (CLBP) in older adults may be disabling and therapeutically challenging, largely because of the inefficacy and/or morbidity associated with traditional pain treatment. We conducted a randomized controlled trial in 200 men and women > or = age 65 with CLBP to evaluate the efficacy of percutaneous electrical nerve stimulation (PENS) with and without general conditioning and aerobic exercise (GCAE), for reducing pain and improving physical function. Participants were randomized to receive (1) PENS, (2) control-PENS (brief electrical stimulation to control for treatment expectancy), (3) PENS+GCAE, or (4) control-PENS+GCAE, twice a week for 6 weeks. All four groups experienced significantly reduced pain (range -2.3 to -4.1 on the McGill Pain Questionnaire short form), improved self-reported disability (range -2.1 to -3.0 on Roland scale) and improved gait velocity (0.04-0.07 m/s), sustained at 6 months. The GCAE groups experienced significantly fewer fear avoidance beliefs immediately post-intervention and at 6 months than non-GCAE groups. There were no significant side effects. Since brief electrical stimulation (i.e., control-PENS) facilitated comparably reduced pain and improved function at 6 months as compared with PENS, the exact dose of electrical stimulation required for analgesia cannot be determined. GCAE was more effective than PENS alone in reducing fear avoidance beliefs, but not in reducing pain or in improving physical function.

Indexed as

AgedChronic DiseaseCombined Modality TherapyElectric Stimulation TherapyExercise TherapyFemaleHumansLow Back PainMalePain MeasurementTreatment Outcome

Identifiers

PMID18930352
PMCPMC2864648
OpenAlexW2014851224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.