ReviewFEBS letters2008
Lipid rafts and T-lymphocyte function: implications for autoimmunity.
Review in FEBS letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 88 citations in OpenAlex.
- The Role of Lipid Rafts in the Mitogen-Activated Protein Kinase Signaling in Cancer.Current medicinal chemistry · 2026Review
- Plasma apolipoprotein A-I is a causal protective factor in sepsis.Scientific reports · 2025Article
- High-density Lipoprotein Cholesterol and the Development of Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue.Journal of cancer prevention · 2025Article
- Protective Effects of High-Density Lipoprotein on Cancer Risk: Focus on Multiple Myeloma.Biomedicines · 2024Review
- NEU1 and NEU3 enzymes alter CD22 organization on B cells.Biophysical reports · 2022Article
- Gangliosides in T cell development and function of mice.Glycoconjugate journal · 2022Review
- Lipid profile changes in patients with COVID-19 referred to medical centers in Kermanshah, Iran; a case-control study.The Journal of international medical research · 2022Article
- Association between cardiometabolic risk factors and COVID-19 susceptibility, severity and mortality: a review.Journal of diabetes and metabolic disorders · 2021Review
- HDL and persistent inflammation immunosuppression and catabolism syndrome.Current opinion in lipidology · 2021Review
- LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals.Journal of hematology & oncology · 2020Article
- COVID-19-Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease.Arteriosclerosis, thrombosis, and vascular biology · 2020Article
- Review
- Inflammaging: a new immune-metabolic viewpoint for age-related diseases.Nature reviews. Endocrinology · 2018Review
- ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content.Scientific reports · 2017Article
- Erythropoietin Receptor Signaling and Lipid Rafts.Vitamins and hormones · 2017Review
- Regulation of T cell signalling by membrane lipids.Nature reviews. Immunology · 2016Review
- HDL: Beyond Atheroprotection.Journal of the American Society of Nephrology : JASN · 2016Article
- Platelet and red blood cell interactions and their role in rheumatoid arthritis.Rheumatology international · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Experimental evidence indicates that the mammalian cell membrane is compartmentalized. A structural feature that supports membrane segmentation implicates assemblies of selected lipids broadly referred to as lipid rafts. In T-lymphocytes, lipid rafts are implicated in signalling from the T-cell antigen receptor (TCR) and in localization and function of proteins residing proximal to the receptor. This review summarizes the current literature that deals with lipid raft involvement in T-cell activation and places particular emphasis in recent studies investigating lipid rafts in autoimmunity. The potential of lipid rafts as targets for the development of a new class of immune-modulating compounds is discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.