ReviewCurrent opinion in cell biology2008
Molecular mechanisms of node of Ranvier formation.
Review in Current opinion in cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 128 citations in OpenAlex.
- Volume electron microscopy reveals oligodendrocyte axon selection patterns and spatial assembly of myelin and nodes.iScience · 2026Article
- Identification of a miRNA signature for schizophrenia in plasma-derived extracellular vesicles.bioRxiv : the preprint server for biology · 2026Article
- Risk genes in progressive supranuclear palsy (PSP) affect integrity and function of microtubules.Frontiers in aging · 2026Review
- Sculpting excitable membranes: voltage-gated ion channel delivery and distribution.Nature reviews. Neuroscience · 2025Review
- A Novel Hybrid of Telmisartan and Borneol Ameliorates Neuroinflammation and White Matter Injury in Ischemic Stroke Through ATF3/CH25H Axis.Translational stroke research · 2024Article
- The Node of Ranvier as an Interface for Axo-Glial Interactions: Perturbation of Axo-Glial Interactions in Various Neurological Disorders.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2023Review
- Higher throughput workflow with sensitive, reliable and automatic quantification of myelination in vitro suitable for drug screening.Scientific reports · 2023Article
- Regulation of the E/I-balance by the neural matrisome.Frontiers in molecular neuroscience · 2023Review
- Oligodendrocyte precursor cell transplantation promotes angiogenesis and remyelination via Wnt/Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Case report: Immunoadsorption therapy for anti-caspr1 antibody-associated nodopathy.Frontiers in immunology · 2022Article
- Nodes of Ranvier during development and repair in the CNS.Nature reviews. Neurology · 2020Review
- Independent anterograde transport and retrograde cotransport of domain components of myelinated axons.The Journal of cell biology · 2020Article
- Review
- Demystifying the extracellular matrix and its proteolytic remodeling in the brain: structural and functional insights.Cellular and molecular life sciences : CMLS · 2019Review
- Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model.Neural plasticity · 2019Article
- Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Alterations of Caspr2 and Nav1.6 on myelinated axon damage in a rat model of chronic cerebral hypoperfusion.Experimental and therapeutic medicine · 2017Article
- GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system.Scientific reports · 2017Article
- White matter injury in ischemic stroke.Progress in neurobiology · 2016Review
- Systematic and differential myelination of axon collaterals in the mammalian auditory brainstem.Glia · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Action potential propagation along myelinated nerve fibers requires high-density protein complexes that include voltage-gated Na(+) channels at the nodes of Ranvier. Several complementary mechanisms may be involved in node assembly including: (1) interaction of nodal cell adhesion molecules with the extracellular matrix; (2) restriction of membrane protein mobility by paranodal junctions; and (3) stabilization of ion channel clusters by axonal cytoskeletal scaffolds. In the peripheral nervous system, a secreted glial protein at the nodal extracellular matrix interacts with axonal cell adhesion molecules to initiate node formation. In the central nervous system, both glial soluble factors and paranodal axoglial junctions may function in a complementary manner to contribute to node formation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.