ReviewSeminars in immunopathology2008
The long road to the thymus: the generation, mobilization, and circulation of T-cell progenitors in mouse and man.
Review in Seminars in immunopathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- EdU tracking of leukocyte recruitment in mouse models of ischemic stroke and sterile lung inflammation.Journal of cell science · 2025Article
- The thymus road to a T cell: migration, selection, and atrophy.Frontiers in immunology · 2024Review
- Hematopoietic Stem Cell Development in Mammalian Embryos.Advances in experimental medicine and biology · 2023Review
- Anti-PD-1 Induces M1 Polarization in the Glioma Microenvironment and Exerts Therapeutic Efficacy in the Absence of CD8 Cytotoxic T Cells.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020Article
- From stem cell to immune effector: how adhesion, migration, and polarity shape T-cell and natural killer cell lymphocyte development in vitro and in vivo.Molecular biology of the cell · 2020Review
- Role of early life immune regulation in asthma development.Seminars in immunopathology · 2020Review
- Coevolution of the coagulation and immune systems.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019Review
- Interleukin-21 promotes thymopoiesis recovery following hematopoietic stem cell transplantation.Journal of hematology & oncology · 2017Article
- Evolution of the immune system in humans from infancy to old age.Proceedings. Biological sciences · 2015Review
- E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.Blood · 2013Article
- Stage-specific functions of E-proteins at the β-selection and T-cell receptor checkpoints during thymocyte development.Immunologic research · 2011Article
- Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue.Clinical and experimental immunology · 2011Review
- FADD deficiency impairs early hematopoiesis in the bone marrow.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
- Article
- Eliciting the T cell fate with Notch.Seminars in immunology · 2010Review
- Article
- Article
- Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation.Immunity · 2009Article
- Settling the thymus: immigration requirements.The Journal of experimental medicine · 2009Article
- Untangling the T branch of the hematopoiesis tree.Current opinion in immunology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The majority of T cells develop in the thymus. T-cell progenitors in the thymus do not self-renew and so progenitor cells must be continuously imported from the blood into the thymus to maintain T-cell production. Recent work has shed light on both the identity of the cells that home to the thymus and the molecular mechanisms involved. This review will discuss the cells in the bone marrow and blood that are involved in early thymopoiesis in mouse and man. Understanding the pre-thymic steps in T-cell development may translate into new therapeutics, especially in the field of hematopoietic stem cell transplantation.
Indexed as
Identifiers
18925398What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.