SynthesisThe International journal of artificial organs2008
Bioelectric effect and bacterial biofilms. A systematic review.
Synthesis in The International journal of artificial organs, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 155 citations in OpenAlex.
- Evaluation of dental plaque reduction using microcurrent-emitting toothbrushes in orthodontic patients: a randomized, double-blind, crossover clinical trial.Scientific reports · 2024Trial
- A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-Based Wireless Electroceutical Dressing Compared to Standard-of-Care Treatment Against Acute Trauma and Burn Wound Biofilm Infection.Advances in wound care · 2024Trial
- From Broadband to Single-Tone Stimulation: Frequency-Selective Response ofMicroorganisms · 2026Article
- Ultrasound-stimulated BTO-BSA-gen inhibits implant-associated infections by suppressing bacterial adhesion and potentiating aminoglycosides.Journal of nanobiotechnology · 2026Article
- Electrolytic cleaning as a biofilm control strategy on medical implants: mechanisms, evidence and translational perspectives.Frontiers in microbiology · 2026Review
- Antibacterial Effect of Combined Electrolytic and Chemical Decontamination Methods on Dental Implant Surfaces: In Vitro Study.Clinical oral implants research · 2025Article
- Antibacterial PEEK-Ag Surfaces: Development and In Vitro Evaluation AgainstJournal of functional biomaterials · 2025Article
- Urinary catheters: state of the art and future perspectives - a narrative review.Materials today. Bio · 2025Review
- The Antimicrobial Effect of a Low-Frequency Square Wave Compared to Chlorhexidine.Journal of clinical medicine · 2025Article
- On the effectiveness of electrical characterization of mature Staphylococcal Biofilm.Scientific reports · 2025Article
- Beyond Antibiotics: What the Future Holds.Antibiotics (Basel, Switzerland) · 2024Review
- Characteristics of Metallic Nanoparticles (Especially Silver Nanoparticles) as Anti-Biofilm Agents.Antibiotics (Basel, Switzerland) · 2024Review
- Revealing detrimental effects of various DC electrical energy conditions on different multidrug resistant bacteria: a comprehensive study.Scientific reports · 2024Article
- Electric Current Application on Dental Implant Biofilms: Review.Journal of functional biomaterials · 2024Review
- The effect of dental material type and masticatory forces on periodontitis-derived subgingival microbiomes.Biofilm · 2024Article
- Transcriptomic profiles of Mannheimia haemolytica planktonic and biofilm associated cells.PloS one · 2024Article
- The treatment of bacterial biofilms cultivated on knee arthroplasty implants using the bioelectric effect.Frontiers in bioengineering and biotechnology · 2024Article
- The effect of titanium surface treatment by application of constant potential or current on the viability of pre-osteoblast cells: anFrontiers in bioengineering and biotechnology · 2024Article
- Bioelectric device for effective biofilm inflammation management of dental implants.Scientific reports · 2023Article
- The Alphabet of Nanostructured Polypyrrole.Materials (Basel, Switzerland) · 2023Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Bacteria growing in biofilms cause a wide range of human infections. Biofilm bacteria are resistant to antimicrobics at levels 500 to 5,000 times higher than those needed to kill non-biofilm bacteria. In vitro experiments have shown that electric current can enhance the activity of some antimicrobial agents against certain bacteria in biofilms; this has been termed the ''bioelectric effect''. Direct electrical current has already been safely used in humans for fracture healing. Application of direct electric current with antimicrobial chemotherapy in humans could theoretically abrogate the need to remove the device in device-related infections, a procedure associated with substantial morbidity and cost. In this article, we review what has been described in the literature with regards to the bioelectric effect.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.