ArticleJournal of plant physiology2009
Spermine signaling plays a significant role in the defense response of Arabidopsis thaliana to cucumber mosaic virus.
Article in Journal of plant physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 123 citations in OpenAlex.
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- The MFS transporter BcTpo1 governs the oxidative stress response and infection of Botrytis cinerea.Crop health · 2026Article
- Defence Warriors: Exploring the crosstalk between polyamines and oxidative stress during microbial pathogenesis.Redox biology · 2025Review
- Polyamines Interaction with Gaseous Signaling Molecules for Resilience Against Drought and Heat Stress in Plants.Plants (Basel, Switzerland) · 2025Review
- Comparative metabolomics and transcriptomics provide new insights into florpyrauxifen-benzyl resistance inFrontiers in plant science · 2024Article
- Spermine inhibits PAMP-induced ROS and Ca2+ burst and reshapes the transcriptional landscape of PAMP-triggered immunity in Arabidopsis.Journal of experimental botany · 2023Article
- Exogenous spermine alleviates the negative effects of combined salinity and paraquat in tomato plants by decreasing stress-induced oxidative damage.Frontiers in plant science · 2023Article
- The role of photorespiration in plant immunity.Frontiers in plant science · 2023Review
- Polyamine Oxidase-Generated Reactive Oxygen Species in Plant Development and Adaptation: The Polyamine Oxidase-NADPH Oxidase Nexus.Antioxidants (Basel, Switzerland) · 2022Review
- Putrescine: A Key Metabolite Involved in Plant Development, Tolerance and Resistance Responses to Stress.International journal of molecular sciences · 2022Review
- Spermine reduces the harmful effects of salt stress inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Sugarcane mosaic virus orchestrates the lactate fermentation pathway to support its successful infection.Frontiers in plant science · 2022Article
- Verticillium wilt resistant and susceptible olive cultivars express a very different basal set of genes in roots.BMC genomics · 2021Article
- Article
- Spermine and Spermidine Priming againstBiomolecules · 2021Article
- The unknown soldier in citrus plants: polyamines-based defensive mechanisms against biotic and abiotic stresses and their relationship with other stress-associated metabolites.Plant signaling & behavior · 2020Article
- Article
- Influence of spermine and nitrogen deficiency on growth and secondary metabolites accumulation inEngineering in life sciences · 2019Article
- The Copper Amine Oxidase AtCuAOδ Participates in Abscisic Acid-Induced Stomatal Closure in Arabidopsis.Plants (Basel, Switzerland) · 2019Article
- A novel hydroxycinnamoyl transferase for synthesis of hydroxycinnamoyl spermine conjugates in plants.BMC plant biology · 2019Article
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8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have proposed that the polyamine spermine (Spm) functions as a signaling molecule to evoke defense reactions/cell death in avirulent pathogen-attacked tobacco plants. To understand its molecular basis in depth, Spm-responsive genes in Arabidopsis thaliana were identified by SuperSAGE analysis. Close to 90% of the Spm-responsive genes also responded during cucumber mosaic virus (CMV)-elicited hypersensitive response. Spm modulated the expression of genes of redox components, and genes involved in protein folding and secretion, protein degradation and defense. Two other prominent changes, the coordinately enhanced expression of members of the photorespiration pathway and a diversion in electron flow from the primary electron transfer chain of respiration to an alternative oxidase pathway, occurred in response to Spm. Spm activated the expression of 6 transcription factor genes including ZAT7, ZAT12, AtWRKY40 and AtbZIP60, of which the former three genes' products are currently assigned as components of H(2)O(2) signaling pathway, suggesting the involvement of H(2)O(2) in Spm-triggered responses. Since AtbZIP60 plays a proven master role in the unfolded protein response in Arabidopsis thaliana, it may function to control the expression of genes participating in protein folding and secretion, which were mentioned above. Spm induction and CMV-triggered up-regulation of the genes described mainly coincided and their induction was suppressed by inhibitors of Spm oxidation. Furthermore, treatment with those inhibitors prior to CMV inoculation allowed higher viral multiplication in Arabidopsis thaliana plants. These results support the existence of a Spm-signaling pathway in Arabidopsis thaliana and its significant role in defense against CMV.
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