ArticleCardiovascular diabetology2008
Dyslipidemia in primary care--prevalence, recognition, treatment and control: data from the German Metabolic and Cardiovascular Risk Project (GEMCAS).
Article in Cardiovascular diabetology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 67 citations in OpenAlex.
- The Effect of ACE I/D Polymorphisms Alone and With Concomitant Risk Factors on Coronary Artery Disease.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018Trial
- Proactive multifactorial intervention strategy reduces the risk of cardiovascular disease estimated with region-specific risk assessment models in Pacific Asian patients participating in the CRUCIAL trial.Journal of Korean medical science · 2013Trial
- Achievement of treatment goals for primary prevention of cardiovascular disease in clinical practice across Europe: the EURIKA study.European heart journal · 2011Trial
- Effectiveness of nurse-delivered cardiovascular risk management in primary care: a randomised trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010Trial
- Lipid management and cardiovascular risk assessment: Physician perspectives from seven countries across five WHORegions - insights from the INTERASPIRE study.American journal of preventive cardiology · 2026Article
- Factors associated with major electrocardiographic abnormalities in chagas disease patients: SaMi-trop cohort.International journal of cardiology. Heart & vasculature · 2026Article
- Automated process assessment of primary healthcare for hyperlipidemia: preliminary findings and implications form Anhui, China.Lipids in health and disease · 2025Article
- biobank.cy: the Biobank of Cyprus past, present and future.Scientific reports · 2024Article
- Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar.Molecular genetics & genomic medicine · 2023Article
- Time effect on cardiometabolic risk indicators in patients with bipolar disorder: a longitudinal case-control study.European archives of psychiatry and clinical neuroscience · 2023Article
- The relationship between dyslipidemia and inflammation among adults in east coast China: A cross-sectional study.Frontiers in immunology · 2022Article
- The association of vascular disorders with incident dementia in different age groups.Alzheimer's research & therapy · 2019Article
- Drug Therapy of Dyslipidemia in the Elderly.Drugs & aging · 2019Review
- Cardiovascular risk assessment of dyslipidemic middle-aged adults without overt cardiovascular disease over the period of 2009-2016 in Lithuania.Lipids in health and disease · 2018Article
- Association of FV G1691A Polymorphism but not A4070G With Coronary Artery Disease.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018Article
- Genetic and microbiome influence on lipid metabolism and dyslipidemia.Physiological genomics · 2018Review
- Serum lysophospholipid levels are altered in dyslipidemic hamsters.Scientific reports · 2017Article
- Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals.Aging cell · 2017Article
- Impact of aging on cardiac sympathetic innervation measured byEuropean journal of nuclear medicine and molecular imaging · 2016Article
- Prevalence of chronic diseases among older patients in German general practices.German medical science : GMS e-journal · 2016Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent guidelines from the European Society of Cardiology (ESC) define low thresholds for the diagnosis of dyslipidemia using total cholesterol (TC) and LDL-cholesterol (LDL-C) to guide treatment. Although being mainly a prevention tool, its thresholds are difficult to meet in clinical practice, especially primary care.
methodsIn a nationwide study with 1,511 primary care physicians and 35,869 patients we determined the prevalence of dyslipidemia, its recognition, treatment, and control rates. Diagnosis of dyslipidemia was based on TC and LDL-C. Basic descriptive statistics and prevalence rate ratios, as well as 95% confidence intervals were calculated.
resultsDyslipidemia was highly frequent in primary care (76% overall). 48.6% of male and 39.9% of female patients with dyslipidemia was diagnosed by the physicians. Life style intervention did however control dyslipidemia in about 10% of patients only. A higher proportion (34.1% of male and 26.7% female) was controlled when receiving pharmacotherapy. The chance to be diagnosed and subsequently controlled using pharmacotherapy was higher in male (PRR 1.15; 95%CI 1.12-1.17), in patients with concomitant cardiovascular risk factors, in patients with hypertension (PRR 1.20; 95%CI 1.05-1.37) and cardiovascular disease (PRR 1.46; 95%CI 1.29-1.64), previous myocardial infarction (PRR 1.32; 95%CI 1.19-1.47), and if patients knew to be hypertensive (PRR 1.18; 95%CI 1.04-1.34) or knew about their prior myocardial infarction (PRR 1.17; 95%CI 1.23-1.53).
conclusionThresholds of the ESC seem to be difficult to meet. A simple call for more aggressive treatment or higher patient compliance is apparently not enough to enhance the proportion of controlled patients. A shift towards a multifactorial treatment considering lifestyle interventions and pharmacotherapy to reduce weight and lipids may be the only way in a population where just to be normal is certainly not ideal.
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