Evidence map›Paper›PMID 18855948›Full record

ArticleMacromolecular bioscience2009

Self-assembling diblock copolymers of poly[N-(2-hydroxypropyl)methacrylamide] and a beta-sheet peptide.

Larisa Cristina Radu, Jiyuan Yang, Jindrich Kopecek

Abstract read
In one paragraph

Article in Macromolecular bioscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Bioinspired Histidine⁻ZnBiomimetics (Basel, Switzerland) · 2019
    Article
  4. Article
  5. Article
  6. Smart self-assembled hybrid hydrogel biomaterials.Angewandte Chemie (International ed. in English) · 2012
    Review
  7. Article
  8. Review
  9. HYDROGELS FROM SOFT CONTACT LENSES AND IMPLANTS TO SELF-ASSEMBLED NANOMATERIALS.Journal of polymer science. Part A, Polymer chemistry · 2009
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Larisa Cristina RaduDepartment of Bioengineering, University of Utah, Salt Lake City, Utah 84112, USA.
Jiyuan Yang
Jindrich Kopecek

Funding

HYBRID HYDROGELS SELF-ASSEMBLED FROM GRAFT COPOLYMERSR01EB005288 · NIBIB · UNIVERSITY OF UTAH · PI KOPECEK, JINDRICH H. · 2005 to 2008
$1.2M
NIBIB NIH HHS EB 005288NIBIB NIH HHS R01 EB005288
6 · The paper itself

Abstract

The self-assembly of hybrid diblock copolymers composed of poly(HPMA) and beta-sheet peptide P11 (CH(3)CO-QQRFQWQFEQQ-NH(2)) blocks was investigated. Copolymers were synthesized via thiol-maleimide coupling reaction, by conjugation of semitelechelic poly(HPMA)-SH with maleimide-modified beta-sheet peptide. As expected, CD and CR binding studies showed that the peptide block imposed its beta-sheet structural arrangement on the structure of diblock copolymers. TEM and AFM proved that peptide and these copolymers had the ability to self-assemble into fibrils.

Indexed as

Protein Structure, SecondaryAmino Acid SequenceCircular DichroismMethacrylatesMicroscopy, Atomic ForceMolecular Sequence DataMolecular StructurePeptidesPolymershydroxypropyl methacrylateMethacrylatesPeptidesPolymers

Identifiers

PMID18855948
PMCPMC4599367

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.