Evidence map›Paper›PMID 18855132›Full record

ArticleJournal of assisted reproduction and genetics

Successful twin birth following blastocyst culture of embryos derived from the immotile ejaculated spermatozoa from a patient with primary ciliary dyskinesia: a case report.

Richard J Kordus, Robert L Price, Jeffrey M Davis, Gail F Whitman-Elia

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of assisted reproduction and genetics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Thoughts on the popularity of ICSI.Journal of assisted reproduction and genetics · 2021
    Review
  5. ART strategies in Klinefelter syndrome.Journal of assisted reproduction and genetics · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. A case of Kartagener syndrome with rhinolalia clausa.The Pan African medical journal · 2016
    Article
  11. Article
  12. Article
  13. Kartagener's syndrome: A case series.Lung India : official organ of Indian Chest Society · 2012
    Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Richard J KordusAdvanced Fertility and Reproductive Endocrinology Institute, LLC, 2728 Sunset Blvd, Suite 305, West Columbia, SC 29169, USA. rkordus@ivfwecare.com
Robert L Price
Jeffrey M Davis
Gail F Whitman-Elia
University of South Carolina · USAdvanced Medical Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the ultrastructure of spermatozoa from a patient with complete asthenozoospermia that resulted in live births following blastocyst culture. MATERIALS AND

methodsAnalyses of spermatozoa from a 36 year old patient were performed using light and electron microscopy. The hypo-osmotic swelling test was used to select spermatozoa for intracytoplasmic sperm injection. Embryos were cultured to the blastocyst stage.

results100% of the spermatozoa had dynein arm deficiency with secondary defects varying from 3-17%. Six oocytes were injected; five fertilized normally and one was digynic. All five zygotes formed good quality blastocysts. Three blastocysts were cryopreserved and two blastocysts were transferred. Twin females were born at 37 weeks.

conclusionsThe hypo-osmotic swelling test can be used to select viable immotile ejaculated spermatozoa from a patient with dynein arm deficiency and can produce excellent fertilization rates and blastocyst development resulting in live births.

Indexed as

Sperm Injections, IntracytoplasmicTwinsAdultBlastocystDyneinsEmbryo Culture TechniquesEmbryo TransferFemaleFlagellaHumansKartagener SyndromeMalePregnancySemen AnalysisSpermatozoaSperm MotilityDyneins

Identifiers

PMID18855132
PMCPMC2582095
OpenAlexW1992604856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.