Evidence map›Paper›PMID 18855078›Full record

ArticleIn vitro cellular & developmental biology. Animal

Mycobacterium avium-intracellulare contamination of mammalian cell cultures.

I H Lelong-Rebel, Y Piemont, M Fabre, G Rebel

Abstract read
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In one paragraph

Article in In vitro cellular & developmental biology. Animal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Best practices for detecting and mitigating the risk of cell culture contaminants.In vitro cellular & developmental biology. Animal · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

I H Lelong-RebelEA3430 ULP/CNRS, IRCAD, Hôpitaux Universitaires de Strasbourg BP 426, 67091 Strasbourg Cedex, France. Isabelle.Lelong@ircad.u-strasbg.fr
Y Piemont
M Fabre
G Rebel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium avium contamination has been described as a putative contaminant of nonphagocytic mammalian cells. Screening of numerous cultured nonphagocytic mammalian cell lines revealed the presence of intracellular bacteria that were identified as M. avium-intracellulare. An extensive and critical analysis of the origin of infection, of cure protocols, and of biological manifestations in M. avium-infected cells is presented. As no tremendous visible alteration of turbidity or pH of cell culture media, and no morphological change occurred in most M. avium-infected cell cultures, detection of an infection by these bacteria is rather difficult. Recommendations are given for treatment of irreplaceable cultures and prevention of mycobacterial contamination in a tissue culture facility.

Indexed as

AnimalsAnti-Bacterial AgentsCell Culture TechniquesCell LineCell Line, TumorDogsHot TemperatureHumansHydrogen-Ion ConcentrationMiceMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionMicroscopy, Phase-ContrastMycobacterium avium ComplexRatsAnti-Bacterial Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.