Trial reportSurgical endoscopy2009
Transgastric endoscopic peritoneoscopy does not require decontamination of the stomach in humans.
Trial report in Surgical endoscopy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 63 citations in OpenAlex.
- Oral chlorhexidine and microbial contamination during endoscopy: possible implications for transgastric surgery. A randomized, clinical trial.Surgical endoscopy · 2013Trial
- Comparison of a novel endoscopic approach versus laparoscopic deroofing for symptomatic simple hepatic cysts.Surgical endoscopy · 2025Article
- Risk of infection after iatrogenic perforation of the gut wall? Evaluation of preventive strategies in a randomized controlled animal trial.Surgical endoscopy · 2016Article
- Review of Pure Endoscopic Full-Thickness Resection of the Upper Gastrointestinal Tract.Gut and liver · 2015Review
- Endoscopic ultrasound-assisted direct peritoneal visualization with a small-caliber scope: A proof of concept study in a swine model.Endoscopic ultrasound · 2014Article
- Non-exposed endoscopic wall-inversion surgery as a novel partial gastrectomy technique.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2014Observational
- Natural orifice transluminal endoscopic surgery and upper gastrointestinal tract.Journal of gastric cancer · 2013Review
- Perioperative inflammatory response in natural orifice translumenal endoscopic surgery.Surgical endoscopy · 2013Article
- Euro-NOTES Status Paper: from the concept to clinical practice.Surgical endoscopy · 2013Article
- An ex vivo bacteriologic study comparing antiseptic techniques for natural orifice translumenal endoscopic surgery (NOTES) via the gastrointestinal tract.Digestive diseases and sciences · 2012Article
- Natural orifice translumenal endoscopic surgery in humans: a review.Minimally invasive surgery · 2012Article
- Transgastric endoscopic pneumoperitoneum versus laparoscopy: effects on host systemic and peritoneal inflammatory responses in a porcine model.Surgical endoscopy · 2012Article
- Transgastric endoscopic peritoneoscopy does not lead to increased risk of infectious complications.Surgical endoscopy · 2011Article
- Natural orifice translumenal endoscopic surgery: progress in humans since white paper.World journal of gastroenterology · 2011Review
- A review of 130 humans enrolled in transgastric NOTES protocols at a single institution.Surgical endoscopy · 2011Review
- Hybrid NOTES transgastric cholecystectomy with reliable gastric closure: an animal survival study.Surgical endoscopy · 2011Article
- Disinfection of the Access Orifice in NOTES: Evaluation of the Evidence Base.Diagnostic and therapeutic endoscopy · 2011Article
- The diagnostic efficacy of natural orifice transluminal endoscopic surgery: is there a role in the intensive care unit?Surgical endoscopy · 2010Article
- Natural orifice transluminal endoscopic surgery in pancreatic diseases.World journal of gastroenterology · 2010Review
- Transgastric cholecystectomy: From the laboratory to clinical implementation.World journal of gastrointestinal surgery · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNatural orifice translumenal endoscopic surgery (NOTES) is a rapidly evolving field that provides endoscopic access to the peritoneum via a natural orifice. One important requirement of this technique is the need to minimize the risk of clinically significant peritoneal contamination. We report the bacterial load and contamination of the peritoneal cavity in ten patients who underwent diagnostic transgastric endoscopic peritoneoscopy.
methodsPatients participating in this trial were scheduled to undergo diagnostic laparoscopy for evaluation of presumed pancreatic cancer. Findings at diagnostic laparoscopy were compared with those of diagnostic transgastric endoscopic peritoneoscopy, using an orally placed gastroscope, blinding the endoscopist to the laparoscopic findings. We performed no gastric decontamination. Diagnostic findings, operative times, and clinical course were recorded. Gastroscope and peritoneal fluid aspirates were obtained prior to and after the gastrotomy. Each sample was sent for bacterial colony counts, culture, and identification of species.
resultsTen patients, with an average age of 63.7 years, have completed the protocol. All patients underwent diagnostic laparoscopy followed by successful transgastric access and diagnostic peritoneoscopy. The average time for laparoscopy was 7.2 min, compared with 18 min for transgastric instrumentation. Bacterial sampling was obtained in all ten patients. The average number of colony-forming units (CFU) in the gastroscope aspirate was 132.1 CFU/ml, peritoneal aspirates prior to creation of a gastrotomy showed 160.4 CFU/ml, and peritoneal sampling after gastrotomy had an average of 642.1 CFU/ml. There was no contamination of the peritoneal cavity with species isolated from the gastroscope aspirate. No infectious complications or leaks were noted at 30-day follow-up.
conclusionsThere was no clinically significant contamination of the peritoneal cavity from the gastroscope after transgastric endoscopic instrumentation in humans. Transgastric instrumentation does contaminate the abdominal cavity but, the pathogens do not mount a clinically significant response in terms of either the species or the bacterial load.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.