ReviewClinical microbiology reviews2008
Adenoviruses in immunocompromised hosts.
Review in Clinical microbiology reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
207 citing papers in PubMed, 2 syntheses or guidelines pooled it, 510 citations in OpenAlex.
- Current Trends of Human Adenovirus Types Among Hospitalized Children-A Systematic Review.Viruses · 2025Pooled it
- Nucleic Acid-based Testing for Noninfluenza Viral Pathogens in Adults with Suspected Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2021Guideline
- Genotypes and phylogenetic analysis of adenovirus in children with respiratory infection in Buenos Aires, Argentina (2000-2018).PloS one · 2021Trial
- Trial
- Pharmacokinetics and safety of intravenous cidofovir for life-threatening viral infections in pediatric hematopoietic stem cell transplant recipients.Antimicrobial agents and chemotherapy · 2015Trial
- Adenovirus infection associated with focal segmental glomerulosclerosis following autologous hematopoietic stem cell transplantation.CEN case reports · 2026Article
- Identification and Characterization of a Novel Bovine Adenovirus Which Represents a Distinct Evolutionary Branch.Viruses · 2026Article
- Late-Onset Adenovirus-Induced Achalasia in a Kidney Transplant Recipient: A Case Report.The American journal of case reports · 2026Article
- Adenoviral Vectors in Gene Therapy: A Detailed Overview.Iranian biomedical journal · 2026Review
- Human adenovirus in Taiwan, 2019-2023.Archives of virology · 2025Article
- Severe Disseminated Adenovirus Infection After Haploidentical Hematopoietic Stem Cell Transplantation: A Case Report.The American journal of case reports · 2025Article
- Analytical and Clinical Evaluation of the AltoStar Adenovirus PCR Kit 1.5 and the AltoStar Automation System AM16 for Adenovirus Detection in Plasma and Stool Samples.The Journal of molecular diagnostics : JMD · 2025Article
- Analysis of factors influencing mortality in immunocompetent children with severe adenovirus pneumonia undergoing conventional treatments: a retrospective cohort study.Translational pediatrics · 2025Article
- Medical Comorbidities as the Independent Risk Factors of Severe Adenovirus Respiratory Tract Infection in Adults.Microorganisms · 2025Article
- Evaluation of factors relating to the development of multiple subepithelial corneal infiltrates of adenoviral keratoconjunctivitis using categorical data analysis program.Japanese journal of ophthalmology · 2025Article
- Article
- Bacterial-like inflammatory response in children with adenovirus leads to inappropriate antibiotic use: a multicenter cohort study.Infection · 2025Article
- Rapid and sensitive detection of human adenovirus types 3 and 7 using CRISPR-Cas12b coupled with multiple cross displacement amplification.Infectious medicine · 2025Article
- Activated blood-derived human primary T cells support replication of HAdV C5 and virus transmission to polarized human primary epithelial cells.Journal of virology · 2025Article
- [Analysis of Adenovirus Detection Trends in the Republic of Korea (2023-2024)].Jugan geon-gang gwa jilbyeong · 2025Article
147 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryThe number of patients with acquired immunodeficiency has grown steadily as a result of both a larger number of patients receiving solid organ and hematopoietic stem cell transplants and their longer survival times. The use of newer, more potent immunosuppressive regimens has increased the frequency of severe adenovirus infections. Human adenoviruses are a large group of viruses, represented by at least 52 serotypes with various genotypes divided into genomic clusters, and these may cause a broad variety of clinical manifestations. The development of molecular methods has increased the sensitivity and rapidity of adenovirus infection diagnosis. The implementation of PCR assays has significantly contributed to the identification of patients with disseminated adenovirus disease. More recently, the development of real-time PCR assays has permitted virus quantification and patient follow-up. There is no treatment for adenovirus with demonstrated efficacy, although cidofovir is widely used. Sensitive diagnostic tests for adenovirus can contribute to the early diagnosis and successful treatment of life-threatening adenovirus infections, especially in complex immunocompromised patients. The development of improved adenovirus therapy still remains a challenge. Adenovirus genetic diversity should be considered for diagnosis, typing, and therapeutic interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.