Evidence map›Paper›PMID 18854485›Full record

ReviewClinical microbiology reviews2008

New insights on classification, identification, and clinical relevance of Blastocystis spp.

Kevin S W Tan

Open access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 342 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
342citing papers in PubMed, 4 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

342 citing papers in PubMed, 4 syntheses or guidelines pooled it, 699 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Medical Parasitology Taxonomy Update, 2016-2017.Journal of clinical microbiology · 2019
    Pooled it
  4. Pooled it
  5. MappingOne health (Amsterdam, Netherlands) · 2026
    Article
  6. Article
  7. Article
  8. ExploringJournal of medical microbiology · 2026
    Review
  9. Blastocystis, an Enigmatic Parasite.Acta parasitologica · 2026
    Review
  10. Article
  11. Article
  12. Occurrence and subtyping of the intestinal protozoanFood and waterborne parasitology · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Commensal, pathogen, or passenger? Rethinking the role ofOne health (Amsterdam, Netherlands) · 2025
    Review
  18. Article
  19. Article
  20. Molecular Identification ofJournal of clinical medicine · 2025
    Article

282 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kevin S W TanDepartment of Microbiology, Laboratory of Molecular and Cellular Parasitology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore. mictank@nus.edu.sg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryBlastocystis is an unusual enteric protozoan parasite of humans and many animals. It has a worldwide distribution and is often the most commonly isolated organism in parasitological surveys. The parasite has been described since the early 1900s, but only in the last decade or so have there been significant advances in our understanding of Blastocystis biology. However, the pleomorphic nature of the parasite and the lack of standardization in techniques have led to confusion and, in some cases, misinterpretation of data. This has hindered laboratory diagnosis and efforts to understand its mode of reproduction, life cycle, prevalence, and pathogenesis. Accumulating epidemiological, in vivo, and in vitro data strongly suggest that Blastocystis is a pathogen. Many genotypes exist in nature, and recent observations indicate that humans are, in reality, hosts to numerous zoonotic genotypes. Such genetic diversity has led to a suggestion that previously conflicting observations on the pathogenesis of Blastocystis are due to pathogenic and nonpathogenic genotypes. Recent epidemiological, animal infection, and in vitro host-Blastocystis interaction studies suggest that this may indeed be the case. This review focuses on such recent advances and also provides updates on laboratory and clinical aspects of Blastocystis spp.

Indexed as

AnimalsBlastocystisBlastocystis InfectionsHumans

Identifiers

PMID18854485
PMCPMC2570156
OpenAlexW2116269514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.