Evidence map›Paper›PMID 18854483›Full record

ReviewClinical microbiology reviews2008

Candida parapsilosis, an emerging fungal pathogen.

David Trofa, Attila Gácser, Joshua D Nosanchuk

Open access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 351 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
351citing papers in PubMed, 1 pooled it
17.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

351 citing papers in PubMed, 1 synthesis or guideline pooled it, 845 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Macrophage activation syndrome triggered by Candida parapsilosis-related cochlear implant infection.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Sporotrichoid lymphocutaneous infection caused byMedical mycology case reports · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The metabolic trap:Journal of medical microbiology · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. The Gut-Vagina Axis.Microorganisms · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

291 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

David TrofaAlbert Einstein College of Medicine, Bronx, NY 10461, USA.
Attila Gácser
Joshua D Nosanchuk
University of Szeged · HUYeshiva University · US

Funding

Immunology/Pathology CoreP30AI051519 · NIAID · YESHIVA UNIVERSITY · PI GOLDSTEIN, HARRIS · 2003 to 2013
$18.6M
Biology of Fungal MelaninR01AI052733 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 2003 to 2019
$6.6M
Antibody Protection in HistoplamosisR01AI056070 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI NOSANCHUK, JOSHUA D · 2005 to 2009
$1.8M
NIAID NIH HHS AI056070-01A2NIAID NIH HHS AI-51519NIAID NIH HHS AI52733NIAID NIH HHS P30 AI051519NIAID NIH HHS R01 AI052733NIAID NIH HHS R01 AI056070
6 · The paper itself

Abstract

summaryCandida parapsilosis is an emerging major human pathogen that has dramatically increased in significance and prevalence over the past 2 decades, such that C. parapsilosis is now one of the leading causes of invasive candidal disease. Individuals at the highest risk for severe infection include neonates and patients in intensive care units. C. parapsilosis infections are especially associated with hyperalimentation solutions, prosthetic devices, and indwelling catheters, as well as the nosocomial spread of disease through the hands of health care workers. Factors involved in disease pathogenesis include the secretion of hydrolytic enzymes, adhesion to prosthetics, and biofilm formation. New molecular genetic tools are providing additional and much-needed information regarding C. parapsilosis virulence. The emerging information will provide a deeper understanding of C. parapsilosis pathogenesis and facilitate the development of new therapeutic approaches for treating C. parapsilosis infections.

Indexed as

CandidaCandidiasisCross InfectionHumansPrevalenceVirulence FactorsVirulence Factors

Identifiers

PMID18854483
PMCPMC2570155
OpenAlexW2099241550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.