ReviewChromosoma2009
Chromatin domains in higher eukaryotes: insights from genome-wide mapping studies.
Review in Chromosoma, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 54 citations in OpenAlex.
- Nuclear Compartments: An Incomplete Primer to Nuclear Compartments, Bodies, and Genome Organization Relative to Nuclear Architecture.Cold Spring Harbor perspectives in biology · 2022Review
- DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders.International journal of molecular sciences · 2022Review
- X Inactivation and Escape: Epigenetic and Structural Features.Frontiers in cell and developmental biology · 2019Review
- The Role of Transcription Factors at Antisense-Expressing Gene Pairs in Yeast.Genome biology and evolution · 2016Article
- Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation.The EMBO journal · 2015Article
- Epigenetic control of immunity.Cold Spring Harbor perspectives in biology · 2014Article
- Segmental folding of chromosomes: a basis for structural and regulatory chromosomal neighborhoods?BioEssays : news and reviews in molecular, cellular and developmental biology · 2013Article
- Divergence of mammalian higher order chromatin structure is associated with developmental loci.PLoS computational biology · 2013Article
- Review
- Article
- A computational model for histone mark propagation reproduces the distribution of heterochromatin in different human cell types.PloS one · 2013Article
- Mapping of lamin A- and progerin-interacting genome regions.Chromosoma · 2012Article
- G-NEST: a gene neighborhood scoring tool to identify co-conserved, co-expressed genes.BMC bioinformatics · 2012Article
- Amplified genes may be overexpressed, unchanged, or downregulated in cervical cancer cell lines.PloS one · 2012Article
- Specific positioning of the casein gene cluster in active nuclear domains in luminal mammary epithelial cells.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2011Article
- Article
- The Chriz-Z4 complex recruits JIL-1 to polytene chromosomes, a requirement for interband-specific phosphorylation of H3S10.Journal of biosciences · 2011Article
- Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity.PLoS genetics · 2011Article
- Advancing our understanding of functional genome organisation through studies in the fission yeast.Current genetics · 2011Review
- Chromatin dynamics and the repair of DNA double strand breaks.Cell cycle (Georgetown, Tex.) · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In genomes of higher eukaryotes, adjacent genes often show coordinated regulation of their expression. Compartmentalization of multiple neighboring genes into a shared chromatin environment can facilitate this coordinated expression. New mapping techniques have begun to reveal that such multigene chromatin domains are a common feature of fly and mammalian genomes. Many different types of chromatin domains have been identified based on the genomic binding patterns of various proteins and histone modifications. In addition, maps of genome-nuclear lamina associations and of looping interactions between loci provide the first systematic views of the three-dimensional folding of interphase chromosomes. These genome-wide datasets uncover new architectural principles of eukaryotic genomes and indicate that multigene chromatin domains are prevalent and important regulatory units.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.