Trial reportRheumatology international2009
Serum antioxidants and nitric oxide levels in fibromyalgia: a controlled study.
Trial report in Rheumatology international, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Proteomics in Patients with Fibromyalgia Syndrome: A Systematic Review of Observational Studies.Current pain and headache reports · 2024Pooled it
- Effects of acupuncture on oxidative stress mechanisms, pain, and quality of life in fibromyalgia: A prospective study from Türkiye.Turkish journal of physical medicine and rehabilitation · 2025Article
- Proprotein convertase subtilisin/kexin type 9 and apelin in fibromyalgia syndrome.Archives of rheumatology · 2024Article
- Predictive Ability of Serum Amino Acid Levels to Differentiate Fibromyalgia Patients from Healthy Subjects.Molecular diagnosis & therapy · 2024Article
- Serum paraoxonase activities, nitric oxide, and malondialdehyde levels are altered in patients with primary fibromyalgia syndrome.Irish journal of medical science · 2023Article
- Melatonin as a Coadjuvant in the Treatment of Patients with Fibromyalgia.Biomedicines · 2023Review
- Oxidative stress involves phenotype modulation of morbid soreness symptoms in fibromyalgia.RMD open · 2023Article
- Contribution of microvascular dysfunction to chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2023Review
- The relationship between dietary total antioxidant capacity, clinical parameters, and oxidative stress in fibromyalgia syndrome: A novel point of view.Turkish journal of physical medicine and rehabilitation · 2022Article
- Article
- Nitric oxide, lipid peroxidation products, and antioxidants in primary fibromyalgia and correlation with disease severity.Journal of medical biochemistry · 2020Article
- Does whole body vibration exercise improve oxidative stress markers in women with fibromyalgia?Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
- Dynamic Thiol/Disulphide Homeostasis in Patients With Fibromyalgia.Archives of rheumatology · 2017Article
- Ambroxol for the treatment of fibromyalgia: science or fiction?Journal of pain research · 2017Article
- Effects of 12-week combined exercise therapy on oxidative stress in female fibromyalgia patients.Rheumatology international · 2014Article
- A quest for better understanding of biochemical changes in fibromyalgia syndrome.Indian journal of clinical biochemistry : IJCB · 2014Article
- Coenzyme Q10 depletion in medical and neuropsychiatric disorders: potential repercussions and therapeutic implications.Molecular neurobiology · 2013Review
- Genetic variations in interleukin-8 and interleukin-10 are associated with pain, depressed mood, and fatigue in lung cancer patients.Journal of pain and symptom management · 2013Article
- The relationship between serum antioxidant vitamins, magnesium levels, and clinical parameters in patients with primary fibromyalgia syndrome.Clinical rheumatology · 2011Article
- Pathophysiology and antioxidant status of patients with fibromyalgia.Rheumatology international · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We proposed to assess antioxidant status and nitric oxide in fibromyalgia (FM) patients in comparison to healthy controls. Additionally, the association between the serum antioxidant levels and clinical findings in FM patients was also investigated. Thirty-seven FM patients and 37 healthy controls were enrolled in this study. Severity of fatigue and pain were determined by Visual Analogue Scale. Functional capacity in daily living activities was evaluated by fibromyalgia impact questionnaire. Serum NO, catalase and glutathione were measured. Serum glutathione and catalase levels were significantly lower in FM patients than controls. However, no significant difference was seen in serum NO levels between the two groups. A significant correlation was evident between serum NO level and pain. Additionally, the correlation between glutathione level and morning stiffness was found to be significant. These findings support other studies, we assume that these two antioxidants might have impact on the pathogenesis of FM disease.
Indexed as
Identifiers
18853166What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.