Evidence map›Paper›PMID 18853141›Full record

Trial reportIntensive care medicine2009

Noninvasive ventilation for acute respiratory failure after lung resection: an observational study.

Aurélie Lefebvre, Christine Lorut, Marco Alifano, Hervé Dermine, Nicolas Roche, Rémy Gauzit, Jean-François Regnard, Gérard Huchon, Antoine Rabbat

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Continuous positive airway pressure (CPAP) after lung resection: a randomized clinical trial.Sao Paulo medical journal = Revista paulista de medicina · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aurélie LefebvreDepartment of Respiratory and Intensive Care Medicine, Hôtel-Dieu Hospital, AP-HP, Université Paris 5, René Descartes, Paris, France.
Christine Lorut
Marco Alifano
Hervé Dermine
Nicolas Roche
Rémy Gauzit
Jean-François Regnard
Gérard Huchon
Antoine Rabbat

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA single prospective randomized study found that, in selected patients with acute respiratory failure (ARF) following lung resection, noninvasive ventilation (NIV) decreases the need for endotracheal mechanical ventilation and improves clinical outcome.

methodWe prospectively evaluated early NIV use for ARF after lung resection during a 4-year period in the setting of a medical and a surgical ICU of a university hospital. We documented demographics, initial clinical characteristics and clinical outcomes. NIV failure was defined as the need for tracheal intubation.

resultsAmong 690 patients at risk of severe complications following lung resection, 113 (16.3%) experienced ARF, which was initially supported by NIV in 89 (78.7%), including 59 with hypoxemic ARF (66.3%) and 30 with hypercapnic ARF (33.7%). The overall success rate of NIV was 85.3% (76/89). In-ICU mortality was 6.7% (6/89). The mortality rate following NIV failure was 46.1%. Predictive factors of NIV failure in univariate analysis were age (P = 0.046), previous cardiac comorbidities (P = 0.0075), postoperative pneumonia (P = 0.0016), admission in the surgical ICU (P = 0.034), no initial response to NIV (P < 0.0001) and occurrence of noninfectious complications (P = 0.037). Only two independent factors were significantly associated with NIV failure in multivariate analysis: cardiac comorbidities (odds ratio, 11.5; 95% confidence interval, 1.9-68.3; P = 0.007) and no initial response to NIV (odds ratio, 117.6; 95% confidence interval, 10.6-1305.8; P = 0.0001).

conclusionThis prospective survey confirms the feasibility and efficacy of NIV in ARF following lung resection.

Indexed as

Postoperative ComplicationsRespiratory InsufficiencyThoracic Surgical ProceduresAcute DiseaseFemaleHumansLungMaleMiddle AgedObservationProspective StudiesPulmonary Disease, Chronic ObstructiveRespiration, Artificial

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.