Evidence map›Paper›PMID 18852277›Full record

ArticleAntimicrobial agents and chemotherapy2009

Efficacy of ciprofloxacin and moxifloxacin against Nocardia brasiliensis in vitro and in an experimental model of actinomycetoma in BALB/c mice.

Brenda Edith Chacon-Moreno, Oliverio Welsh, Norma Cavazos-Rocha, Maria de la Luz Salazar-Cavazos, Hector Gerardo Garza-Lozano, Salvador Said-Fernandez, Jorge Ocampo-Candiani, Lucio Vera-Cabrera

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Mycetoma medical therapy.PLoS neglected tropical diseases · 2014
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Brenda Edith Chacon-MorenoServicio de Dermatología, Hospital Universitario José E. González, Monterrey, NL, Mexico.
Oliverio Welsh
Norma Cavazos-Rocha
Maria de la Luz Salazar-Cavazos
Hector Gerardo Garza-Lozano
Salvador Said-Fernandez
Jorge Ocampo-Candiani
Lucio Vera-Cabrera
Hospital Universitario Dr José Eleuterio Gonzalez · MXUniversidad Autónoma de Nuevo León · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of ciprofloxacin and moxifloxacin against Nocardia brasiliensis was evaluated by applying 25 mg of each drug/kg subcutaneously every 8 h in BALB/c mice infected with N. brasiliensis. A statistically significant difference was observed only with moxifloxacin. A moxifloxacin-trimethoprim-sulfamethoxazole combination was as active as when each compound was used alone.

Indexed as

AnimalsAza CompoundsCiprofloxacinDisease Models, AnimalFemaleFluoroquinolonesMiceMice, Inbred BALB CMicrobial Sensitivity TestsMoxifloxacinMycetomaNocardiaQuinolinesAza CompoundsCiprofloxacinFluoroquinolonesMoxifloxacinQuinolines

Identifiers

PMID18852277
PMCPMC2612135
OpenAlexW2089365754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.