Evidence map›Paper›PMID 18851754›Full record

Trial reportBMC geriatrics2008

Frailty Intervention Trial (FIT).

Nicola Fairhall, Christina Aggar, Susan E Kurrle, Catherine Sherrington, Stephen Lord, Keri Lockwood, Noeline Monaghan, Ian D Cameron

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03824106 (Frailty Rehabilitation), which is not on this map. Cited by 64 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 8 pooled it
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03824106 narecruitingnot on this mapstarted 2022, after this paper: background citation

Frailty Rehabilitation: A Community-based Intervention to Promote Healthy Aging

TypeinterventionalSponsorMcMaster UniversityRan2022 to 2025Enrolled324ConditionsFrailtyArmsControl, Group Exercise, Nutrition and Medication review, Protein Supplement, Vitamin D
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 8 syntheses or guidelines pooled it, 161 citations in OpenAlex.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nicola FairhallRehabilitation Studies Unit, Faculty of Medicine, The University of Sydney, Sydney Australia. nfairhall@george.org.au
Christina Aggar
Susan E Kurrle
Catherine Sherrington
Stephen Lord
Keri Lockwood
Noeline Monaghan
Ian D Cameron
University of Sydney · AUHornsby Ku-ring-gai Hospital · AUNeuroscience Research Australia · AUThe George Institute for Global Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrailty is a term commonly used to describe the condition of an older person who has chronic health problems, has lost functional abilities and is likely to deteriorate further. However, despite its common use, only a small number of studies have attempted to define the syndrome of frailty and measure its prevalence. The criteria Fried and colleagues used to define the frailty syndrome will be used in this study (i.e. weight loss, fatigue, decreased grip strength, slow gait speed, and low physical activity). Previous studies have shown that clinical outcomes for frail older people can be improved using multi-factorial interventions such as comprehensive geriatric assessment, and single interventions such as exercise programs or nutritional supplementation, but no interventions have been developed to specifically reverse the syndrome of frailty.We have developed a multidisciplinary intervention that specifically targets frailty as defined by Fried et al. We aim to establish the effects of this intervention on frailty, mobility, hospitalisation and institutionalisation in frail older people. METHODS AND

designA single centre randomised controlled trial comparing a multidisciplinary intervention with usual care. The intervention will target identified characteristics of frailty, functional limitations, nutritional status, falls risk, psychological issues and management of chronic health conditions. Two hundred and thirty people aged 70 and over who meet the Fried definition of frailty will be recruited from clients of the aged care service of a metropolitan hospital. Participants will be followed for a 12-month period. DISCUSSION: This research is an important step in the examination of specifically targeted frailty interventions. This project will assess whether an intervention specifically targeting frailty can be implemented, and whether it is effective when compared to usual care. If successful, the study will establish a new approach to the treatment of older people at risk of further functional decline and institutionalisation. The strategies to be examined are readily transferable to routine clinical practice and are applicable broadly in the setting of aged care health services.

trial registrationAustralian New Zealand Clinical Trails Registry: ACTRN12608000250336.

Indexed as

Activities of Daily LivingFrail ElderlyMobility LimitationAccidental FallsAgedAged, 80 and overAge FactorsAustraliaCognition DisordersFatigueFemaleFractures, BoneGeriatric AssessmentHospitalizationHumansLogistic Models

Identifiers

PMID18851754
PMCPMC2579913
OpenAlexW2017537727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.