ArticlePhysical review letters2008
Actin bundling: initiation mechanisms and kinetics.
Article in Physical review letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Efficient simulation of thermally fluctuating biopolymers immersed in fluids on 1-micron, 1-second scales.Journal of computational physics · 2019Article
- Diamond, graphite, and graphene oxide nanoparticles decrease migration and invasiveness in glioblastoma cell lines by impairing extracellular adhesion.International journal of nanomedicine · 2017Article
- Numerical Approach to Spatial Deterministic-Stochastic Models Arising in Cell Biology.PLoS computational biology · 2016Article
- Assembly kinetics determine the architecture of α-actinin crosslinked F-actin networks.Nature communications · 2012Article
- Model of myosin node aggregation into a contractile ring: the effect of local alignment.Journal of physics. Condensed matter : an Institute of Physics journal · 2011Article
- Modeling the formation of in vitro filopodia.Journal of mathematical biology · 2011Article
- The Eps8/IRSp53/VASP network differentially controls actin capping and bundling in filopodia formation.PLoS computational biology · 2011Article
- Quantifying a pathway: kinetic analysis of actin dendritic nucleation.Biophysical journal · 2010Article
- Use of virtual cell in studies of cellular dynamics.International review of cell and molecular biology · 2010Review
- The role of actin bundling proteins in the assembly of filopodia in epithelial cells.Cell adhesion & migrationReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Bundling of rapidly polymerizing actin filaments underlies the dynamics of filopodial protrusions that play an important role in cell migration and cell-cell interaction. Recently, the formation of actin bundles has been reconstituted in vitro, and two scenarios of bundle initiation, involving binding of two filament tips and, alternatively, linking of the tip of one filament to the side of the other, have been discussed. A first theoretical analysis is presented indicating that the two mechanisms can be distinguished experimentally. While both of them result counterintuitively in comparable numbers of bundles, these numbers scale differently with the average bundle length. We propose an experiment for determining which of the two mechanisms is involved in the in vitro bundle formation.
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Registered trials
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