ArticlePhysical review letters2008
Strain softening in stretched DNA.
Article in Physical review letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed.
- RLDOCKScore: A Scoring Function for RNA-Ligand Docking and Small Molecule Virtual Screening.Journal of chemical theory and computation · 2025Article
- Article
- Understanding protein diffusion on force-induced stretched DNA conformation.Frontiers in molecular biosciences · 2022Article
- Microtubule instability driven by longitudinal and lateral strain propagation.PLoS computational biology · 2020Article
- Explicit ions/implicit water generalized Born model for nucleic acids.The Journal of chemical physics · 2018Article
- Melting of polymeric DNA double helix at elevated temperature: a molecular dynamics approach.Journal of molecular modeling · 2017Article
- Understanding the mechanical response of double-stranded DNA and RNA under constant stretching forces using all-atom molecular dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Opposing Effects of Multivalent Ions on the Flexibility of DNA and RNA.Physical review letters · 2016Article
- DNA exit ramps are revealed in the binding landscapes obtained from simulations in helical coordinates.PLoS computational biology · 2015Article
- Electronic detection of dsDNA transition from helical to zipper conformation using graphene nanopores.Nanotechnology · 2014Article
- Close encounters with DNA.Journal of physics. Condensed matter : an Institute of Physics journal · 2014Review
- The transition mechanism of DNA overstretching: a microscopic view using molecular dynamics.Journal of the Royal Society, Interface · 2014Article
- Microsecond simulations of DNA and ion transport in nanopores with novel ion-ion and ion-nucleotides effective potentials.Journal of computational chemistry · 2014Article
- Toward detection of DNA-bound proteins using solid-state nanopores: insights from computer simulations.Electrophoresis · 2012Article
- Predicting the DNA sequence dependence of nanopore ion current using atomic-resolution Brownian dynamics.The journal of physical chemistry. C, Nanomaterials and interfaces · 2012Article
- B-DNA to zip-DNA: simulating a DNA transition to a novel structure with enhanced charge-transport characteristics.The journal of physical chemistry. A · 2011Article
- Mechanical properties of a complete microtubule revealed through molecular dynamics simulation.Biophysical journal · 2010Article
- Analyzing the forces binding a restriction endonuclease to DNA using a synthetic nanopore.Nucleic acids research · 2009Article
- Molecular diagnostics for personal medicine using a nanopore.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnologyReview
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The microscopic mechanics of DNA stretching was characterized using extensive molecular dynamics simulations. By employing an anisotropic pressure-control method, realistic force-extension dependences of effectively infinite DNA molecules were obtained. A coexistence of B and S DNA domains was observed during the overstretching transition. The simulations revealed that strain softening may occur in the process of stretching torsionally constrained DNA. The latter observation was qualitatively reconciled with available experimental data using a random-field Ising model.
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Registered trials
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