ArticleMolecular biology reports2009
Response of cementoblast-like cells to mechanical tensile or compressive stress at physiological levels in vitro.
Article in Molecular biology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 34 citations in OpenAlex.
- HK2-mediated Glycolysis Inhibits Mineralization of Cementoblasts Under Compression by Suppressing the Piezo1/Wnt Signaling.International journal of medical sciences · 2025Article
- Orthodontic tension promotes cementoblast mineralization by regulating autophagy.Journal of dental sciences · 2024Article
- 3D-Printed Polycaprolactone-Based Containing Calcium Zirconium Silicate: Bioactive Scaffold for Accelerating Bone Regeneration.Polymers · 2024Article
- Establishment ofExperimental and therapeutic medicine · 2020Article
- Long noncoding RNA expression profile of mouse cementoblasts under compressive force.The Angle orthodontist · 2019Article
- [Effect of sclerostin on the functions and related mechanisms of cementoblasts under mechanical stress].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2019Article
- Role of osteopontin in bone remodeling and orthodontic tooth movement: a review.Progress in orthodontics · 2018Review
- Cementogenesis is inhibited under a mechanical static compressive force via Piezo1.The Angle orthodontist · 2017Article
- Intermittent parathyroid hormone (PTH) promotes cementogenesis and alleviates the catabolic effects of mechanical strain in cementoblasts.BMC cell biology · 2017Article
- Screening the Expression Changes in MicroRNAs and Their Target Genes in Mature Cementoblasts Stimulated with Cyclic Tensile Stress.International journal of molecular sciences · 2016Article
- Overexpression of osteopontin in hepatocellular carcinoma and its relationships with metastasis, invasion of tumor cells.Molecular biology reports · 2011Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To clarify the role of cementoblast in orthodontic-related root resorption, this study was attempted to examine whether murine cementoblast-like cells are responsive to mechanical stress, and how mechanical forces regulate bone sialoprotein (BSP) and osteopontin (OPN) gene expression in these cells in vitro. In this force-loading model, defined and reproducible mechanical loadings of different magnitudes and types were applied up to 24 h. Besides a transitory and reversible change in cell proliferation, remarkable alterations in gene transcription of BSP and OPN were found. BSP mRNA was suppressed by the stresses. Three and six hours-loadings at 2,000 microstrain up-regulated the expression of OPN mRNA, while the other loadings inhibited it. The study also concluded that 4,000 microstrain was likely to exert more influence on cementoblast-like cells than 2,000 microstrain. Furthermore, no obvious evidence indicated the difference between tension and compression. These results suggested that cementoblast-like cells are sensitive to mechanical stress, and may play a role in regulating orthodontic-related root resorption/repair.
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