ArticleThe Plant cell2008
Transgenic Arabidopsis plants expressing the type 1 inositol 5-phosphatase exhibit increased drought tolerance and altered abscisic acid signaling.
Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.
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Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 158 citations in OpenAlex.
- Uncovering core regulators of multi-abiotic stress adaptation in Arabidopsis thaliana through integrative meta-analysis and machine learning with RT-qPCR validation.Scientific reports · 2026Pooled it
- Pooled it
- Integrating image-based phenotyping and GWAS to map resistance to spittlebug nymphs in interspecific Urochloa grasses.G3 (Bethesda, Md.) · 2026Article
- Synergistic melatonin and myo-inositol application reinforces antioxidant defence, osmotic homeostasis, and membrane stability in Western Himalayan apple rootstocks under drought stress.BMC plant biology · 2026Article
- Metabolite-mediated enhancement of drought resilience in north-western Himalayan apple rootstocks through synergistic modulation of physiological performance.Scientific reports · 2026Article
- Sugar alcohols in plants: implications for enhancing tree seedlings drought tolerance and production strategies.BMC plant biology · 2025Review
- KRN5b regulates maize kernel row number through mediating phosphoinositol signalling.Plant biotechnology journal · 2024Article
- Modulation of the wheat transcriptome by TaZFP13D under well-watered and drought conditions.Plant molecular biology · 2024Article
- Phosphoinositides in plant-pathogen interaction: trends and perspectives.Stress biology · 2023Review
- Comparative transcriptome analysis reveals molecular regulation of salt tolerance in two contrasting chickpea genotypes.Frontiers in plant science · 2023Article
- The functions of phospholipases and their hydrolysis products in plant growth, development and stress responses.Progress in lipid research · 2022Review
- The Indole-3-Acetamide-InducedFrontiers in plant science · 2022Article
- Foliar Application of an Inositol-Based Plant Biostimulant Boosts Zinc Accumulation in Wheat Grains: A μ-X-Ray Fluorescence Case Study.Frontiers in plant science · 2022Article
- Phospholipases C and D and Their Role in Biotic and Abiotic Stresses.Plants (Basel, Switzerland) · 2021Review
- Estimating the number of protein molecules in a plant cell: protein and amino acid homeostasis during drought.Plant physiology · 2021Article
- Common bean SNP alleles and candidate genes affecting photosynthesis under contrasting water regimes.Horticulture research · 2021Article
- Ectopic Expression ofInternational journal of molecular sciences · 2020Article
- Transcriptome Analysis of Drought-Resistant and Drought-Sensitive Sorghum (International journal of molecular sciences · 2020Article
- Draft genome sequence of Solanum aethiopicum provides insights into disease resistance, drought tolerance, and the evolution of the genome.GigaScience · 2019Article
- The Function of Inositol Phosphatases in Plant Tolerance to Abiotic Stress.International journal of molecular sciences · 2019Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phosphoinositide pathway and inositol-1,4,5-trisphosphate (InsP(3)) are implicated in plant responses to stress. To determine the downstream consequences of altered InsP(3)-mediated signaling, we generated transgenic Arabidopsis thaliana plants expressing the mammalian type I inositol polyphosphate 5-phosphatase (InsP 5-ptase), which specifically hydrolyzes soluble inositol phosphates and terminates the signal. Rapid transient Ca(2+) responses to a cold or salt stimulus were reduced by approximately 30% in these transgenic plants. Drought stress studies revealed, surprisingly, that the InsP 5-ptase plants lost less water and exhibited increased drought tolerance. The onset of the drought stress was delayed in the transgenic plants, and abscisic acid (ABA) levels increased less than in the wild-type plants. Stomatal bioassays showed that transgenic guard cells were less responsive to the inhibition of opening by ABA but showed an increased sensitivity to ABA-induced closure. Transcript profiling revealed that the drought-inducible ABA-independent transcription factor DREB2A and a subset of DREB2A-regulated genes were basally upregulated in the InsP 5-ptase plants, suggesting that InsP(3) is a negative regulator of these DREB2A-regulated genes. These results indicate that the drought tolerance of the InsP 5-ptase plants is mediated in part via a DREB2A-dependent pathway and that constitutive dampening of the InsP(3) signal reveals unanticipated interconnections between signaling pathways.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.