ArticleProceedings of the National Academy of Sciences of the United States of America2008
A membrane-tethered transcription factor defines a branch of the heat stress response in Arabidopsis thaliana.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers.
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Who cites it
136 citing papers in PubMed, 275 citations in OpenAlex.
- SRF6, a heat-inducible receptor-like kinase, regulates thermotolerance in Arabidopsis thaliana.Plant cell reports · 2026Article
- A Review of Nuclear-Organellar Communication in Response to Heat Stress.Plants (Basel, Switzerland) · 2026Review
- FaCPK19-FaTT1 axis decodes heat-induced CaThe New phytologist · 2026Article
- Signal peptide peptidase-like proteases OsSPPL1 and OsSPPL2 facilitate ER-associated protein degradation in rice.Nature communications · 2026Article
- Anther and pollen thermotolerance: molecular mechanisms and implications for plant reproduction under heat stress.Planta · 2026Review
- The OsMADS18-OsbZIP60 module plays a critical role in influencing grain chalkiness in rice.Science China. Life sciences · 2026Article
- bZIP factors of the Unfolded Protein Response interact with PIF4 to promote thermomorphogenesis.Nature communications · 2025Article
- The bZIP transcription factor RISBZ1 balances grain filling and ER stress response in rice grains.Plant communications · 2025Article
- The core morning clock component CCA1 enhances UPR target gene expression to facilitate ER stress recovery.Plant communications · 2025Article
- Polyamines Interaction with Gaseous Signaling Molecules for Resilience Against Drought and Heat Stress in Plants.Plants (Basel, Switzerland) · 2025Review
- VvFHY3 links auxin and endoplasmic reticulum stress to regulate grape anthocyanin biosynthesis at high temperatures.The Plant cell · 2024Article
- Programmed cell death regulator BAP2 is required for IRE1-mediated unfolded protein response in Arabidopsis.Nature communications · 2024Article
- Dynamics of ER stress-induced gene regulation in plants.Nature reviews. Genetics · 2024Review
- PtWRKY2, a WRKY transcription factor from Pinellia ternata confers heat tolerance in Arabidopsis.Scientific reports · 2024Article
- Melatonin-Regulated Chaperone Binding Protein Plays a Key Role in Cadmium Stress Tolerance in Rice, Revealed by the Functional Characterization of a Novel SerotoninInternational journal of molecular sciences · 2024Article
- Calcium Signaling and the Response to Heat Shock in Crop Plants.International journal of molecular sciences · 2023Review
- Genome-wide identification of bZIP gene family and expression analysis of BhbZIP58 under heat stress in wax gourd.BMC plant biology · 2023Article
- Crosstalk between endoplasmic reticulum and cytosolic unfolded protein response in tomato.Cell stress & chaperones · 2023Article
- Geminivirus satellite-encoded βC1 activates UPR, induces bZIP60 nuclear export, and manipulates the expression of bZIP60 downstream genes to benefit virus infection.Science China. Life sciences · 2023Article
- Article
76 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, heat stress responses are controlled by heat stress transcription factors that are conserved among all eukaryotes and can be constitutively expressed or induced by heat. Heat-inducible transcription factors that are distinct from the "classical" heat stress transcription factors have also been reported to contribute to heat tolerance. Here, we show that bZIP28, a gene encoding a putative membrane-tethered transcription factor, is up-regulated in response to heat and that a bZIP28 null mutant has a striking heat-sensitive phenotype. The heat-inducible expression of genes that encode BiP2, an endoplasmic reticulum (ER) chaperone, and HSP26.5-P, a small heat shock protein, is attenuated in the bZIP28 null mutant. An estradiol-inducible bZIP28 transgene induces a variety of heat and ER stress-inducible genes. Moreover, heat stress appears to induce the proteolytic release of the predicted transcription factor domain of bZIP28 from the ER membrane, thereby causing its redistribution to the nucleus. These findings indicate that bZIP28 is an essential component of a membrane-tethered transcription factor-based signaling pathway that contributes to heat tolerance.
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