Evidence map›Paper›PMID 18848884›Full record

ReviewCurrent opinion in immunology2008

Towards a cure for food allergy.

Justin M Skripak, Hugh A Sampson

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Gatekeepers of intestinal inflammation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Justin M SkripakMount Sinai School of Medicine, New York, NY, United States.
Hugh A Sampson
Icahn School of Medicine at Mount Sinai · US

Funding

Tolerance vs. Allergenicity; Factors Dictating Differing ResponsesU19AI044236 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SAMPSON, HUGH A · 2008 to 2014
$9.8M
NIAID NIH HHS U19 AI044236
6 · The paper itself

Abstract

Over the past two decades, food allergies have become both more prevalent and long lasting. This burgeoning problem has not been met with any therapeutic options to date, and patients must attempt to avoid known allergenic foods and treat any allergic reactions with 'as-needed' medications. There are a number of promising emerging therapeutic modalities for food allergy, including allergen-specific and allergen non-specific immunotherapeutic approaches. Although the allergen-specific approaches have some distinct differences, they all attempt to induce tolerance by exposing the patient to an allergen via the mucosal route (oral tolerance induction). Allergen non-specific approaches include biologics to suppress free total IgE levels (e.g. anti-IgE antibody) or to induce more general immune suppression (Chinese herbal medication).

Indexed as

Administration, OralAdministration, SublingualAllergensDesensitization, ImmunologicDrugs, Chinese HerbalFood HypersensitivityHumansImmunoglobulin ERecombinant ProteinsAllergensDrugs, Chinese HerbalImmunoglobulin ERecombinant Proteins

Identifiers

PMID18848884
PMCPMC2605785
OpenAlexW2137747253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.