ArticleAnalytical biochemistry2009
The interaction of biological and noxious transition metals with the zinc probes FluoZin-3 and Newport Green.
Article in Analytical biochemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Cellular Uptake, Intracellular Fate, and Cytotoxicity of Micro- and Nanoparticulate Nickel Substances in Human Lung Cells.Chemical research in toxicology · 2026Article
- A redox- and proton-coupled inner membrane transporter mediates copper import to the bacterial cytoplasm.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Metal selectivity and translocation mechanism characterization in proteoliposomes of the transmembrane NiCoT transporter NixA fromChemical science · 2024Article
- Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes.Analytical chemistry · 2022Article
- Spontaneous, synchronous zinc spikes oscillate with neural excitability and calcium spikes in primary hippocampal neuron culture.Journal of neurochemistry · 2021Article
- Probing the Structure and Function of the Cytosolic Domain of the Human Zinc Transporter ZnT8 with Nickel(II) Ions.International journal of molecular sciences · 2021Article
- Principles and practice of determining metal-protein affinities.The Biochemical journal · 2021Review
- Nanoscale battery cathode materials induce DNA damage in bacteria.Chemical science · 2020Article
- Using FluoZin-3 and fura-2 to monitor acute accumulation of free intracellular CdBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2019Article
- In Vitro and in Cellulo Sensing of Transition Metals Using Time-Resolved Fluorescence Spectroscopy and Microscopy.Journal of fluorescence · 2019Article
- Role of Calprotectin in Withholding Zinc and Copper from Candida albicans.Infection and immunity · 2018Article
- Proton-dependent zinc release from intracellular ligands.Journal of neurochemistry · 2014Article
- Fluorescence lifetime imaging of physiological free Cu(II) levels in live cells with a Cu(II)-selective carbonic anhydrase-based biosensor.Metallomics : integrated biometal science · 2014Article
- Selectivity and specificity of small molecule fluorescent dyes/probes used for the detection of Zn2+ and Ca2+ in cells.Metallomics : integrated biometal science · 2014Article
- Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Transient Influx of nickel in root mitochondria modulates organic acid and reactive oxygen species production in nickel hyperaccumulator Alyssum murale.The Journal of biological chemistry · 2013Article
- Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles.ACS nano · 2011Article
- Imaging mobile zinc in biology.Current opinion in chemical biology · 2010Review
- A turn-on fluorescent sensor for detecting nickel in living cells.Journal of the American Chemical Society · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Zinc-sensitive fluorescent probes have become increasingly important in the investigation of the cellular roles of zinc. There is, however, little information on how the other transition metals in cells may influence the measurement of zinc. We have characterized in vitro the interaction of the nominal zinc indicators FluoZin-3 and Newport Green with all the cationic transition metals found within cells, Cr, Mn, Fe, Co, and Cu, as well as Ni and Cd, by measuring their dissociation constants. In addition, we have shown how FluoZin-3 can be used to quantify the concentration of copper in a cell-free assay and report that the fluorescence of Newport Green is boosted by both Cu(I) and Fe(II). Furthermore, we have introduced diagnostics for detecting the interference of metals other than zinc with its measurement within cells.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.