ArticleTobacco control2009
An algorithm for tailoring pharmacotherapy for smoking cessation: results from a Delphi panel of international experts.
Article in Tobacco control, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Treatment of Smoking Lapses and Relapses
Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care
Who cites it
17 citing papers in PubMed.
- Bupropion and naltrexone for smoking cessation: A double-blind randomized placebo-controlled clinical trial.Clinical pharmacology and therapeutics · 2016Trial
- An Algorithm Approach to Determining Smoking Cessation Treatment for Persons Living With HIV/AIDS: Results of a Pilot Trial.Journal of acquired immune deficiency syndromes (1999) · 2015Trial
- Nicotine patch vs. nicotine lozenge for smoking cessation: an effectiveness trial coordinated by the Community Clinical Oncology Program.Drug and alcohol dependence · 2010Trial
- Building consensus on a set of ENDS-specific pictorial health warnings: a Delphi study among a tobacco control expert panel.Tobacco control · 2025Article
- Combining default choices and an encounter decision aid to improve tobacco cessation in primary care patients: protocol for a cluster-randomized trial.BMC primary care · 2022Article
- Between wellness, relapse, and remission: Stages of illness in anorexia nervosa.The International journal of eating disorders · 2020Article
- Delphi study among international expert panel to develop waterpipe-specific health warning labels.Tobacco control · 2020Article
- Steps of care for adolescents with anorexia nervosa-A Delphi study.The International journal of eating disorders · 2019Article
- Effectiveness of Switching Smoking-Cessation Medications Following Relapse.American journal of preventive medicine · 2017Article
- A Pilot Trial Examining African American and White Responses to Algorithm-Guided Smoking Cessation Medication Selection in Persons Living with HIV.AIDS and behavior · 2017Article
- Refining compliance surveys to measure the smokefree status of jurisdictions using the Delphi method.Public health action · 2013Article
- Intersection of Smoking, Human immunodeficiency virus/acquired immunodeficiency syndrome and Cancer: Proceedings of the 8(th) Annual Texas Conference on Health Disparities.Journal of carcinogenesis · 2013Review
- Article
- Smoking cessation for the neurologic patient.Neurology. Clinical practice · 2012Article
- Nicotine dependence and psychological distress: outcomes and clinical implications in smoking cessation.Psychology research and behavior management · 2011Article
- Smoking cessation quitlines in Europe: matching services to callers' characteristics.BMC public health · 2010Article
- Smoking and chronic obstructive pulmonary disease (COPD). Parallel epidemics of the 21 century.International journal of environmental research and public health · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence-based smoking cessation guidelines recommend nicotine replacement therapy (NRT), bupropion SR and varenicline as first-line therapy in combination with behavioural interventions. However, there are limited data to guide clinicians in recommending one form over another, using combinations, or matching individual smokers to particular forms.
objectiveTo develop decision rules for clinicians to guide differential prescribing practices and tailoring of pharmacotherapy for smoking cessation.
methodsA Delphi approach was used to build consensus among a panel of 37 international experts from various health disciplines. Through an iterative process, panellists responded to three rounds of questionnaires. Participants identified and ranked "best practices" used by them to tailor pharmacotherapy to aid smoking cessation. An independent panel of 10 experts provided cross-validation of findings.
resultsThere was a 100% response rate to all three rounds. A high level of consensus was achieved in determining the most important priorities: (1) factors to consider in prescribing pharmacotherapy: evidence, patient preference, patient experience; (2) combinations based on: failed attempt with monotherapy, patients with breakthrough cravings, level of tobacco dependence; (3) specific combinations, main categories: (a) two or more forms of NRT, (b) bupropion + form of NRT; (4) specific combinations, subcategories: (1a) patch + gum, (1b) patch + inhaler, (1c) patch + lozenge; (2a) bupropion + patch, (2b) bupropion + gum; (5) impact of comorbidities on selection of pharmacotherapy: contraindications, specific pharmacotherapy useful for certain comorbidities, dual purpose medications; (6) frequency of monitoring determined by patient needs and type of pharmacotherapy.
conclusionAn algorithm and guide were developed to assist clinicians in prescribing pharmacotherapy for smoking cessation. There appears to be good justification for "off-label" use such as higher doses of NRT or combination therapy in certain circumstances. This practical tool reflects best evidence to date of experts in tobacco cessation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.