Evidence map›Paper›PMID 18843735›Full record

SynthesisThe Cochrane database of systematic reviews2008

Electromechanical and robot-assisted arm training for improving arm function and activities of daily living after stroke.

Jan Mehrholz, Thomas Platz, Joachim Kugler, Marcus Pohl

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02496026 (Transcranial Direct Current Stimulation and Robotic Therapy in Upper Limb Motor Recovery After Stroke), which is not on this map. Cited by 66 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02496026 nacompletednot on this mapstarted 2014, after this paper: background citation

Transcranial Direct Current Stimulation and Robotic Therapy in Upper Limb Motor Recovery After Stroke

TypeinterventionalSponsorAuxilium Vitae VolterraRan2014 to 2017Enrolled20ConditionsStrokeArmstDCS plus wrist robot therapy, Sham tDCS plus wrist robot therapy
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  6. Mirror therapy for improving motor function after stroke.The Cochrane database of systematic reviews · 2012
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  8. Simultaneous bilateral training for improving arm function after stroke.The Cochrane database of systematic reviews · 2010
    Pooled it
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  10. Dissociating motor learning from recovery in exoskeleton training post-stroke.Journal of neuroengineering and rehabilitation · 2018
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jan MehrholzWissenschaftliches Institut, Private Europäische Medizinische Akademie der Klinik Bavaria in Kreischa GmbH, Kreischa, Germany. jan.mehrholz@klinik-bavaria.de
Thomas Platz
Joachim Kugler
Marcus Pohl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElectromechanical and robot-assisted arm training devices are used in rehabilitation and might help to improve arm function after stroke.

objectivesTo assess the effectiveness of electromechanical and robot-assisted arm training for improving activities of daily living and arm function and motor strength of patients after stroke, and the acceptability and safety of the therapy. SEARCH STRATEGY: We searched the Cochrane Stroke Group Trials Register (last searched October 2007), the Cochrane Central Register of Controlled Trials (The Cochrane Library, Issue 3, 2007), MEDLINE (1950 to October 2007), EMBASE (1980 to October 2007), CINAHL (1982 to October 2007), AMED (1985 to October 2007), SPORTDiscus (1949 to October 2007), PEDro (searched October 2007), COMPENDEX (1972 to October 2007) and INSPEC (1969 to October 2007). We also handsearched relevant conference proceedings, searched trials and research registers, checked reference lists, and contacted trialists, experts and researchers in our field, and manufacturers of commercial devices. SELECTION CRITERIA: Randomised controlled trials comparing electromechanical and robot-assisted arm training for recovery of arm function with other rehabilitation interventions or no treatment for patients after stroke. DATA COLLECTION AND ANALYSIS: Two review authors independently selected trials for inclusion, assessed trial quality and extracted data. We contacted trialists for additional information. We analysed the results as standardised mean differences (SMDs) for continuous variables and relative risk differences (RD) for dichotomous variables. MAIN

resultsWe included 11 trials (328 participants) in this review. Electromechanical and robot-assisted arm training did not improve activities of daily living (SMD = 0.29; 95% confidence interval (CI) -0.47 to 1.06; P = 0.45; I(2 )= 85%). Arm motor function and arm motor strength improved (SMD = 0.68, 95% CI 0.24 to 1.11; P = 0.002; I(2 )= 56% and SMD = 01.03, 95% CI 0.29 to 1.78; P = 0.007; I(2 )= 79% respectively). Electromechanical and robot-assisted arm training did not increase the risk of patients to drop out (RD) (fixed-effect model) = 0.01; 95% CI -0.05 to 0.06; P = 0.77; I(2 )= 0.0%) and adverse events were rare. AUTHORS'

conclusionsPatients who receive electromechanical and robot-assisted arm training after stroke are not more likely to improve their activities of daily living, but arm motor function and strength of the paretic arm may improve. However, the results must be interpreted with caution because there were variations between the trials in the duration, amount of training and type of treatment, and in the patient characteristics.

Indexed as

Activities of Daily LivingArtificial LimbsRoboticsStroke RehabilitationExercise TherapyHumansRandomized Controlled Trials as TopicRecovery of FunctionUpper Extremity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.