Evidence map›Paper›PMID 18843629›Full record

SynthesisThe Cochrane database of systematic reviews2008

Dressings for superficial and partial thickness burns.

Jason Wasiak, Heather Cleland, Fiona Campbell

2 registry-linked trialsAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02318056 nawithdrawnnot on this mapstarted 2015, after this paper: background citation

The Burn Glove Trial-A Randomized Controlled Trial of Dressings for Partial Thickness Hand Burns

TypeinterventionalSponsorSouthern Illinois UniversityRan2015 to 2016Enrolled0ConditionsBurnsArmsAquacel® Ag Burn Glove, Mepilex® Transfer Ag, antibiotic
NCT03564795 naterminatednot on this mapstarted 2018, after this paper: background citation

Effectiveness of KeraStat Gel for Improved Cosmesis of Partial Thickness Burns

TypeinterventionalSponsorKeraNetics, LLCRan2018 to 2023Enrolled14ConditionsPartial-thickness BurnArmsKeraStat Gel, Silver Sulfadiazine
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Interventions for treating leg ulcers in people with sickle cell disease.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Pooled it
  3. Interventions for treating leg ulcers in people with sickle cell disease.The Cochrane database of systematic reviews · 2014
    Pooled it
  4. Antibiotic prophylaxis for preventing burn wound infection.The Cochrane database of systematic reviews · 2013
    Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jason WasiakVictorian Adult Burns Service, Alfred Hospital, Commercial Road , Prahran, Melbourne, Victoria, Australia, 3181. J.Wasiak@alfred.org.au
Heather Cleland
Fiona Campbell

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn acute burn wound is a complex and evolving injury. Extensive burns produce, in addition to local tissue damage, systemic consequences. Treatment of partial thickness burn wounds is directed towards promoting healing, and a wide variety of dressings is currently available. Improvements in technology and advances in understanding of wound healing have driven the development of new dressings. Dressing selection should be based on their effects of healing, but ease of application and removal, dressing change requirements, cost and patient comfort should also be considered.

objectivesTo assess the effects of burn wound dressings for superficial and partial thickness burns. SEARCH STRATEGY: We searched the Cochrane Wounds Group Specialised Register (Searched 29/5/08); The Cochrane Central Register of Controlled Trials (CENTRAL) - The Cochrane Library Issue 2 2008; Ovid MEDLINE - 1950 to May Week 3 2008; Ovid EMBASE - 1980 to 2008 Week 21 and Ovid CINAHL - 1982 to May Week 4 2008. SELECTION CRITERIA: All randomised controlled trials (RCTs) that evaluated the effects of burn wound dressings for superficial and partial thickness burns. DATA COLLECTION AND ANALYSIS: Two authors using standardised forms extracted the data independently. Each trial was assessed for internal validity with differences resolved by discussion. MAIN

resultsA total of 26 RCTs are included in this review and most were methodologically poor. A number of dressings appear to have some benefit over other products in the management of superficial and partial thickness burns. This benefit relates to time to wound healing, the number of dressing changes and the level of pain experienced. The use of biosynthetic dressings is associated with a decrease in time to healing and reduction in pain during dressing changes. The use of silver sulphadiazine (SSD) as a comparator on burn wounds for the full duration of treatment needs to be reconsidered, as a number of studies showed delays in time to wound healing and increased number of dressing applications in patients treated with SSD dressings. AUTHORS'

conclusionsThere is a paucity of high quality RCTs on dressings for superficial and partial thickness burn injury. The studies summarised in this review evaluated a variety of interventions, comparators and clinical endpoints. Despite some potentially positive findings, the evidence, which largely derives from trials with methodological shortcomings, is of limited usefulness in aiding clinicians in choosing suitable treatments.

Indexed as

Wound HealingBandagesBurnsHumansRandomized Controlled Trials as Topic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.