Evidence map›Paper›PMID 18843527›Full record

ArticleJournal of genetic counseling2009

Is there a significant trend in prevalence of consanguineous marriage in Tehran? A review of three generations.

Seyed Mohammad Akrami, Vahideh Montazeri, Somaieh Rashid Shomali, Ramin Heshmat, Bagher Larijani

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Article in Journal of genetic counseling, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Genetics and genomic medicine in Iran.Molecular genetics & genomic medicine · 2019
    Article
  9. Consanguineous Marriage as a Risk Factor for Developing Keratoconus.Medical hypothesis, discovery & innovation ophthalmology journal · 2018
    Article
  10. Consanguinity Among Parents of Iranian Deaf Children.Iranian Red Crescent medical journal · 2016
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Mutation analysis of the CYP21A2 gene in the Iranian population.Genetic testing and molecular biomarkers · 2012
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seyed Mohammad AkramiDepartment of Medical Genetics, Tehran University of Medical Sciences, Poursina St., Tehran, 14176, Iran. akramism@tums.ac.ir
Vahideh Montazeri
Somaieh Rashid Shomali
Ramin Heshmat
Bagher Larijani

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consanguineous marriage is a common practice in Iran. The present study surveyed the trend in consanguineous marriage across three generations of Iranians. Index cases, consisting of 400 individuals attending the diabetes and osteoporosis clinic in Shariati Hospital, were interviewed. Data on consanguinity status for 1789 marriages within the index cases' families were obtained. Generation 1 consisted of marriages contracted before 1948, Generation 2 consisted of marriages contracted between 1949 and 1978, and Generation 3 consisted of marriages contracted after 1979. Prevalence of consanguineous marriage within these three generations was 8.8%, 16.6% and 19%, respectively, and represented a significant trend (p < 0.001). First cousin marriage was the most common type of consanguinity (69%). Socioeconomic level of families was not significantly related to having a consanguineous marriage. These data suggest that premarital genetic counseling and mass media efforts are needed to increase public awareness about genetic risks associated with consanguineous marriage.

Indexed as

ConsanguinityMarriageEducational StatusFemaleHumansIranMalePrevalence

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.