Evidence map›Paper›PMID 18843009›Full record

SynthesisCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2008

Physical activity and pancreatic cancer risk: a systematic review.

Ying Bao, Dominique S Michaud

Open access · bronzeAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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  6. Review
  7. Article
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  11. Physical Activity and Pancreatic Cancer Risk among Urban Chinese: Results from Two Prospective Cohort Studies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018
    Article
  12. Exploring the Linkage between Activity-Friendly Zoning, Inactivity, and Cancer Incidence in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2017
    Article
  13. Statins and pancreatic cancer.Oncology letters · 2017
    Article
  14. Article
  15. Cancer incidence in Canada: trends and projections (1983-2032).Health promotion and chronic disease prevention in Canada : research, policy and practice · 2015
    Review
  16. Review
  17. Article
  18. Review
  19. Plasma 25-hydroxyvitamin D and risk of pancreatic cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2012
    Article
  20. How to reduce your cancer risk: mechanisms and myths.International journal of general medicine · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Ying BaoDepartment of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.
Dominique S Michaud
Harvard University · USImperial College London · GB

Funding

Prospective Cohort Collaborative in Pancreatic Cancer Epidemiology & PathogenesisR01CA124908 · NCI · DANA-FARBER CANCER INST · PI FUCHS, CHARLES S · 2007 to 2012
$4.3M
NCI NIH HHS R01 CA124908
6 · The paper itself

Abstract

backgroundPhysical activity has been associated with a lower risk for pancreatic cancer in several studies, but the overall epidemiologic evidence is not consistent. We therefore did a systematic review to evaluate the association between physical activity and pancreatic cancer risk.

methodsWe searched MEDLINE and EMBASE through April 2008 and examined the reference lists of the retrieved articles. We excluded studies that relied on job titles as surrogate measures for physical activity. We used a random-effects model to pool study-specific risk estimates comparing the highest versus the lowest category of physical activity.

resultsTotal physical activity (occupational and leisure time) was not significantly associated with risk for pancreatic cancer [4 prospective studies; summary relative risk, 0.76, 95% confidence interval (95% CI), 0.53-1.09]. A decreased risk for pancreatic cancer was observed for occupational physical activity (3 prospective studies; relative risk, 0.75; 95% CI, 0.58-0.96) but not for leisure-time physical activity (14 prospective studies; relative risk, 0.94; 95% CI, 0.83-1.05). No association was found with light physical activity (2 prospective studies; relative risk, 1.01; 95% CI, 0.77-1.34), moderate physical activity (6 prospective studies; relative risk, 0.83; 95% CI, 0.58-1.18), or vigorous physical activity (7 prospective studies; relative risk, 0.94; 95% CI, 0.80-1.12).

conclusionsThis systematic review does not provide strong evidence for an association between physical activity and risk for pancreatic cancer.

Indexed as

Motor ActivityHumansPancreatic NeoplasmsRisk Factors

Identifiers

PMID18843009
PMCPMC4896495
OpenAlexW2111864941

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.