Evidence map›Paper›PMID 18842048›Full record

ArticleJournal of the American Chemical Society2008

A diazirine-based nucleoside analogue for efficient DNA interstrand photocross-linking.

Zhihai Qiu, Lianghua Lu, Xing Jian, Chuan He

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Covalent labeling of nucleic acids.Chemical Society reviews · 2020
    Review
  9. Chemically triggered crosslinking with bioorthogonal cyclopropenones.Chemical communications (Cambridge, England) · 2020
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhihai QiuDepartment of Chemistry, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Lianghua Lu
Xing Jian
Chuan He

Funding

Direct Oxidative Nucleic Acids DemethylationR01GM071440 · NIGMS · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2005 to 2018
$3.7M
NIGMS NIH HHS R01 GM071440
6 · The paper itself

Abstract

A diazirine-based nucleoside analogue (DBN) efficiently forms DNA interstand cross-linking under near-UV irradiation. This new base analogue may find broad applications in biotechnology and phototherapy.

Indexed as

DiazomethaneDNAModels, MolecularNucleosidesPhotochemical ProcessesThermodynamicsUltraviolet RaysDiazomethaneDNANucleosides

Identifiers

PMID18842048
PMCPMC2945524

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.