Evidence map›Paper›PMID 18841878›Full record

ArticleJournal of proteome research2008

Proteomic analysis of the hyaloid vascular system regression during ocular development.

Elena Albè, Jin-Hong Chang, Nathalie F Azar, Alexander R Ivanov, Dimitri T Azar

Abstract read
In one paragraph

Article in Journal of proteome research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Proteomic Analysis of Embryonic and Young Human Vitreous.Investigative ophthalmology & visual science · 2015
    Article
  2. Article
  3. Article
  4. Novel aspects of corneal angiogenic and lymphangiogenic privilege.Progress in retinal and eye research · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elena AlbèDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
Jin-Hong Chang
Nathalie F Azar
Alexander R Ivanov
Dimitri T Azar

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MCANANY, JAMES JASON · 1985 to 2025
$14.8M
METALLOPROTEINASE EXPRESSION IN CORNEAL WOUNDSR01EY010101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AZAR, DIMITRI T · 1999 to 2020
$6.5M
Collagen XVIII in Corneal NeovascularizationR01EY014048 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHANG, JIN-HONG · 2003 to 2006
$1.1M
METALLOPROTEINASE EXPRESSION IN CORNEAL WOUNDSR29EY010101 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI AZAR, DIMITRI T. · 1994 to 1998
–
NEI NIH HHS EY14048NEI NIH HHS NIH EY10101NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY010101NEI NIH HHS R01 EY014048PHS HHS P30-001792
6 · The paper itself

Abstract

We describe a proteomic approach to investigate the differential protein expression patterns and identify the physiologically relevant angiogenic and antiangiogenic factors involved in the hyaloid vascular system regression. Differentially expressed proteins were identified using two-dimensional gel electrophoresis followed by nanoflow chromatography coupled with tandem mass spectrometry. These proteins are expected to provide insight as to their function in the early maintenance and eventual regression of the hyaloid vascular system.

Indexed as

Ocular Physiological PhenomenaOrganogenesisAnimalsAnimals, NewbornEyeGene Expression Regulation, DevelopmentalImmunohistochemistryMiceMice, Inbred C57BLProteomeProteomicsProteome

Identifiers

PMID18841878
PMCPMC2662928

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.