Evidence map›Paper›PMID 18841167›Full record

ArticleJournal of exposure science & environmental epidemiology2009

Acute exposure to elevated PM2.5 generated by traffic and cardiopulmonary health effects in healthy older adults.

Zhihua Tina Fan, Qingyu Meng, Clifford Weisel, Robert Laumbach, Pamela Ohman-Strickland, Stuart Shalat, Marta Z Hernandez, Kathleen Black

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Exposure to urban particulate matter and its association with human health risks.Environmental science and pollution research international · 2020
    Review
  6. Review
  7. Levels and health risk assessments of particulate matters (PMEnvironmental science and pollution research international · 2019
    Article
  8. An easily ignored factor for CAN-fine particulate exposure [Letter].Diabetes, metabolic syndrome and obesity : targets and therapy · 2019
    Article
  9. Article
  10. Evaluation of vulnerable PMEnvironmental science and pollution research international · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Analysis of Individual Variations in Autonomic Responses to Urban and Forest Environments.Evidence-based complementary and alternative medicine : eCAM · 2015
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhihua Tina FanEnvironmental and Occupational Health Sciences Institute, Piscataway, New Jersey 08854, USA. zfan@eohsi.rutgers.edu
Qingyu Meng
Clifford Weisel
Robert Laumbach
Pamela Ohman-Strickland
Stuart Shalat
Marta Z Hernandez
Kathleen Black

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI ROBERT John LAUMBACH · 1988 to 2026
$47.4M
NIEHS NIH HHS P30 ES005022NIEHS NIH HHS P30ES005022
6 · The paper itself

Abstract

There are evidences for exposure to vehicular emissions and adverse cardiopulmonary health effects. This study attempted to further explore these effects on elderly. This study monitored personal PM(2.5) concentrations and ambulatory electrocardiograms continuously for 24 h on 1 working day in 3 separate weeks for 11 school crossing guards. Spirometry was also performed before and after the morning shift. The traffic at each work location was video recorded during one of the three morning shifts. The increases in the average personal PM(2.5) concentrations (baseline PM(2.5) was subtracted) of 1.2-87 and 1.1-98 microg/m(3) were observed during the 1-h morning (DeltaPM(2.5-ave-m)) and afternoon shift (DeltaPM(2.5-ave-a)), respectively. Traffic count was not a significant predictor of the DeltaPM(2.5-ave-m) (P=0.78). Mean heart rate variability (HRV), measured as 5-min standard deviation of normal-to-normal (SDNN) beats during the 10-min rest periods, decreased 18-26% (P<0.02) 15 min, 2 and 4 h after the morning shift, but changes in SDNN (DeltaSDNN) were insignificant post-afternoon exposure (-0.3 to -7% with P>0.53). DeltaSDNN were negatively associated with DeltaPM(2.5-ave-m), with the strongest association at 2 h after the morning shift (P<0.01) but insignificant 4 h after the morning exposure. The peak PM(2.5) concentration (DeltaPM(2.5-peak), baseline PM(2.5) was subtracted) was not a significant predictor for DeltaSDNN, and no clear effect of PM(2.5) exposure on heart rate was observed. There was no effect of PM exposure on lung function (P>0.16), either. In conclusion, acute exposure to the PM(2.5) resulting from mobile sources can cause acute decline in HRV in healthy older adults, suggesting one of the biological mechanisms for the adverse cardiovascular health effects associated with traffic-related air pollution. Traffic count may not be an appropriate surrogate measure of acute personal exposure to vehicular emission in traffic congested areas.

Indexed as

Vehicle EmissionsAir PollutantsHeartHumansMiddle AgedParticle SizeRespiratory SystemAir PollutantsVehicle Emissions

Identifiers

PMID18841167
PMCPMC4035692

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.