SNO-hemoglobin and hypoxic vasodilation.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

21 citing papers in PubMed.

1. Defining and quantifying oxygen delivery potency of blood products.Blood red cells & iron · 2026
   Article
2. Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent andJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
   Article
3. Optimized S-nitrosohemoglobin Synthesis in Red Blood Cells to Preserve Hypoxic Vasodilation ViaThe Journal of pharmacology and experimental therapeutics · 2022
   Article
4. Hypoxic vasodilatory defect and pulmonary hypertension in mice lacking hemoglobin β-cysteine93 S-nitrosylation.JCI insight · 2022
   Article
5. Red Blood Cell-Mediated S-Nitrosohemoglobin-Dependent Vasodilation: Lessons Learned from a β-Globin Cys93 Knock-In Mouse.Antioxidants & redox signaling · 2021
   Review
6. Essential Role of Hemoglobin βCys93 in Cardiovascular Physiology.Physiology (Bethesda, Md.) · 2020
   Review
7. Role of Nitric Oxide Carried by Hemoglobin in Cardiovascular Physiology: Developments on a Three-Gas Respiratory Cycle.Circulation research · 2020
   Review
8. Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell.Circulation · 2019
   Article
9. Microcirculation dysfunction in endotoxic shock rabbits is associated with impaired S-nitrosohemoglobin-mediated nitric oxide release from red blood cells: a preliminary study.Intensive care medicine experimental · 2019
   Article
10. HbE/β-Thalassemia and Oxidative Stress: The Key to Pathophysiological Mechanisms and Novel Therapeutics.Antioxidants & redox signaling · 2017
    Review
11. Oxidative Stress in the Healthy and Wounded Hepatocyte: A Cellular Organelles Perspective.Oxidative medicine and cellular longevity · 2016
    Review
12. Regulation of oxygen delivery to the body via hypoxic vasodilation.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
13. Hemoglobin βCys93 is essential for cardiovascular function and integrated response to hypoxia.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
14. Evaluating the capacity to generate and preserve nitric oxide bioactivity in highly purified earthworm erythrocruorin: a giant polymeric hemoglobin with potential blood substitute properties.The Journal of biological chemistry · 2015
    Article
15. Generating S-nitrosothiols from hemoglobin: mechanisms, conformational dependence, and physiological relevance.The Journal of biological chemistry · 2013
    Article
16. S-nitrosylation therapy to improve oxygen delivery of banked blood.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
17. Role of the b93cys, ATP and adenosine in red cell dependent hypoxic vasorelaxation.International journal of physiology, pathophysiology and pharmacology · 2013
    Article
18. What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology.The Journal of biological chemistry · 2010
    Review
19. Neurovascular coupling in rat brain operates independent of hemoglobin deoxygenation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2010
    Article
20. Hemoglobin, nitric oxide and molecular mechanisms of hypoxic vasodilation.Trends in molecular medicine · 2009
    Review

Corrections and comments

• Comment on
  SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation.2008

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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