ArticleEpidemiology and infection2009
Household structure and infectious disease transmission.
Article in Epidemiology and infection, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Systematic Review of Household Transmission of Strep A: A Potential Site for Prevention That Has Eluded Attention.The Journal of infectious diseases · 2024Pooled it
- Incorporating human dynamic populations in models of infectious disease transmission: a systematic review.BMC infectious diseases · 2022Pooled it
- Role-specific household contact patterns in urban and rural China: Implications for influenza household transmission.Infectious Disease Modelling · 2027Article
- An ensemble machine learning approach for predicting anemia among under-five children in malaria-endemic sub-Saharan African countries.Infectious diseases of poverty · 2026Article
- Rubella outbreak investigation in Adigrat town of Eastern Tigray, Northern Ethiopia, 2024: case-control study design.BMC public health · 2026Article
- Relationship between household attributes and contact patterns in urban and rural South Africa.PloS one · 2026Article
- Synthetic population generation with public health characteristics for spatial agent-based models.PLoS computational biology · 2025Article
- Spatio-temporal forecasting of COVID-19 cases in the Netherlands for source and contact tracing.International journal of population data science · 2025Article
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- Reconstructed influenza A/H3N2 infection histories reveal variation in incidence and antibody dynamics over the life course.PLoS biology · 2024Article
- Quantifying age-specific household contacts in Aotearoa New Zealand for infectious disease modelling.Royal Society open science · 2024Article
- Reconstructed influenza A/H3N2 infection histories reveal variation in incidence and antibody dynamics over the life course.medRxiv : the preprint server for health sciences · 2024Article
- Generating synthetic population for simulating the spatiotemporal dynamics of epidemics.PLoS computational biology · 2024Article
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- The role of place-based factors and other social determinants of health on adverse post-sepsis outcomes: a review of the literature.Frontiers in disaster and emergency medicine · 2024Article
- Meat safety knowledge, attitude and practices of slaughterhouse workers in Kajiado, Kenya.Veterinary medicine and science · 2024Article
- Exploring the impact of population ageing on the spread of emerging respiratory infections and the associated burden of mortality.BMC infectious diseases · 2023Article
- The representative COVID-19 cohort Munich (KoCo19): from the beginning of the pandemic to the Delta virus variant.BMC infectious diseases · 2023Article
- Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
One of the central tenets of modern infectious disease epidemiology is that an understanding of heterogeneities, both in host demography and transmission, allows control to be efficiently optimized. Due to the strong interactions present, households are one of the most important heterogeneities to consider, both in terms of predicting epidemic severity and as a target for intervention. We consider these effects in the context of pandemic influenza in Great Britain, and find that there is significant local (ward-level) variation in the basic reproductive ratio, with some regions predicted to suffer 50% faster growth rate of infection than the mean. Childhood vaccination was shown to be highly effective at controlling an epidemic, generally outperforming random vaccination and substantially reducing the variation between regions; only nine out of over 10 000 wards did not obey this rule and these can be identified as demographically atypical regions. Since these benefits of childhood vaccination are a product of correlations between household size and number of dependent children in the household, our results are qualitatively robust for a variety of disease scenarios.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.