ReviewPediatric nephrology (Berlin, Germany)2009
Severe hypertension in children and adolescents: pathophysiology and treatment.
Review in Pediatric nephrology (Berlin, Germany), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed.
- Perioperative Management of Paediatric Hypertension.Children (Basel, Switzerland) · 2025Review
- Article
- Clinical guidelines for the diagnosis, evaluation, and management of hypertension for Korean children and adolescents: the Korean Working Group of Pediatric Hypertension.Kidney research and clinical practice · 2025Article
- Efficacy and safety of fenoldopam for the treatment of hypertensive crises in children with kidney disease: a retrospective study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Treatment of Hypertension in Children.Current hypertension reviews · 2024Review
- Managing severe hypertension in children.Pediatric nephrology (Berlin, Germany) · 2023Review
- Hypertensive emergency occurred due to forgetting to take antihypertensive medication: A case study.SAGE open medical case reports · 2023Article
- Diazoxide-Induced Hypertrichosis in a Neonate With Transient Hyperinsulinism.Clinical medicine insights. Case reports · 2023Article
- Hypertension crisis as the first symptom of renovascular hypertension in children.Italian journal of pediatrics · 2022Article
- Hypertension in Patients with Insulin Resistance: Etiopathogenesis and Management in Children.International journal of molecular sciences · 2022Review
- Management of Acute Kidney Injury in Extremely Low Birth Weight Infants.Frontiers in pediatrics · 2022Review
- Management of Hypertensive Crises in Children: A Review of the Recent Literature.Frontiers in pediatrics · 2022Review
- Hypertensive Crisis in a Pediatric Patient Experiencing Clonidine Withdrawal.Case reports in pediatrics · 2022Article
- Midodrine overdose in children: a case report and review of treatment for hypertensive emergencies.Translational pediatrics · 2021Article
- Pathophysiological clinical features of an infant with hypertension secondary to multicystic dysplastic kidney: a case report.BMC nephrology · 2021Article
- Acute severe hypertension associated with acute gastroenteritis in children.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Pharmacologic Control of Blood Pressure in Infants and Children.Pediatric cardiology · 2020Review
- A Practical Guide to the Management of Severe Hypertension in Children.Paediatric drugs · 2020Article
- Hypertensive Crisis in Pediatric Patients: An Overview.Frontiers in pediatrics · 2020Review
- Hypertensive crisis in children and adolescents.Pediatric nephrology (Berlin, Germany) · 2019Review
Corrections and comments
- Erratum issuedDosage article in article text
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe, symptomatic hypertension occurs uncommonly in children, usually only in those with underlying congenital or acquired renal disease. If such hypertension has been long-standing, then rapid blood pressure reduction may be risky due to altered cerebral hemodynamics. While many drugs are available for the treatment of severe hypertension in adults, few have been studied in children. Despite the lack of scientific studies, some agents, particularly continuous intravenous infusions of nicardipine and labetalol, are preferred in many centers. These agents generally provide the ability to control the magnitude and rapidity of blood pressure reduction and should--in conjunction with careful patient monitoring--allow the safe reduction of blood pressure and the avoidance of complications. This review provides a summary of the underlying causes and pathophysiology of acute severe hypertension in childhood as well as a detailed discussion of drug treatment and the optimal clinical approach to managing children and adolescents with acute severe hypertension.
Indexed as
Identifiers
18839219What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.