ArticleThe Journal of biological chemistry2008
Tomato phenylalanine ammonia-lyase gene family, highly redundant but strongly underutilized.
Article in The Journal of biological chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 112 citations in OpenAlex.
- Identification and preliminary functional characterization of MsPAL2, a key salt-tolerance gene during seed germination in Medicago sativa.BMC plant biology · 2026Article
- Genome-wide analysis and expression profiling of the phenylalanine ammonia-lyase gene family in Chrysanthemum morifolium.BMC plant biology · 2026Article
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- Organic fertilization with cow dung modulates growth, bioactive compounds, and antioxidant capacity in duckweed (Frontiers in plant science · 2026Article
- Pre and postharvest application of regulators enhances bell pepper quality and antioxidant levels during cold storage.Scientific reports · 2025Article
- CRISPR/dCas12a-mediated activation of SlPAL2 enhances tomato resistance against bacterial canker disease.PloS one · 2025Article
- Article
- Enzymatic Characterization ofPlants (Basel, Switzerland) · 2024Article
- Genome-wide identification of the phenylalanine ammonia-lyase gene from Epimedium Pubescens Maxim. (Berberidaceae): novel insight into the evolution of the PAL gene family.BMC plant biology · 2024Article
- Isolation and Characterization ofGenes · 2024Article
- Article
- Insights to Phenylalanine Ammonia Lyase (PAL) and Secondary Metabolism in Orchids: An in silico Approach.Biochemical genetics · 2024Article
- Expression profiling of the phenylalanine ammonia-lyase (Plant signaling & behavior · 2023Article
- Genome-wide identification and expression analysis of phenylalanine ammonia-lyase (PAL) family in rapeseed (Brassica napus L.).BMC plant biology · 2023Article
- Elucidating the Mesocarp Drupe Transcriptome of Açai (International journal of molecular sciences · 2023Article
- Different LED light spectra's and nano-chelated potassium affect the quality traits of Dolce Vita cut roses in soilless culture condition.Scientific reports · 2023Article
- Modulation of lignin biosynthesis for drought tolerance in plants.Frontiers in plant science · 2023Review
- Molecular identification of phenylalanine ammonia lyase-encoding genesFrontiers in plant science · 2023Article
- Article
- Genome-Wide Analysis and Expression Profiling of the Phenylalanine Ammonia-Lyase Gene Family inInternational journal of molecular sciences · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phenylalanine ammonia-lyase (PAL) is an important enzyme in both plant development and pathogen defense. In all plants it is encoded by a multi-gene family, ranging in copy number from four in Arabidopsis to a dozen or more copies in some higher plants. Many studies indicate that alternate genes are differentially regulated in response to environmental stimuli. In this study, Southern blot and dot blot analyses in tomato indicate a surprisingly large family of related sequences with approximately 26 copies in the diploid genome, some easily distinguished by restriction enzyme digestion. Analyses of a BAC genome library suggest that the genes are generally not clustered. A more detailed comparison of the gene sequences using PCR to isolate the individual copies and reverse transcription-PCR to study the transcripts that they encode indicates a significant diversity in the gene sequences themselves, but surprisingly only one mRNA transcript can be detected even when additional expression is induced by pathogen growth or wounding. Consistent with previous reports in other plants, a parallel study with a closely related plant, the potato, indicates a much broader utilization of the PAL genes, highlighting the unusual nature of this family in tomato and of the mechanism(s) that silences so many members. Plant transformation analyses further demonstrate the presence of very active silencing, suggesting aggressive competition between PAL gene duplication and copy inactivation during PAL gene evolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.