ReviewImmunological reviews2008
Immune evasion during foot-and-mouth disease virus infection of swine.
Review in Immunological reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in Mice.Viruses · 2021Article
- Foot-and-Mouth Disease Virus VP3 Protein Acts as a Critical Proinflammatory Factor by Promoting Toll-Like Receptor 4-Mediated Signaling.Journal of virology · 2021Article
- Foot and Mouth Disease Vaccine Development and Challenges in Inducing Long-Lasting Immunity: Trends and Current Perspectives.Veterinary medicine (Auckland, N.Z.) · 2021Review
- A Comprehensive Review of the Immunological Response against Foot-and-Mouth Disease Virus Infection and Its Evasion Mechanisms.Vaccines · 2020Review
- Molecular Mechanisms of Immune Escape for Foot-and-Mouth Disease Virus.Pathogens (Basel, Switzerland) · 2020Review
- Advances in Foot-and-Mouth Disease Virus Proteins Regulating Host Innate Immunity.Frontiers in microbiology · 2020Review
- Type I Interferon Induced and Antagonized by Foot-and-Mouth Disease Virus.Frontiers in microbiology · 2018Review
- Molecular Mechanisms of Foot-and-Mouth Disease Virus Targeting the Host Antiviral Response.Frontiers in cellular and infection microbiology · 2017Review
- Foot-and-mouth disease virus structural protein VP3 degrades Janus kinase 1 to inhibit IFN-γ signal transduction pathways.Cell cycle (Georgetown, Tex.) · 2016Article
- Macrophage Polarization in Virus-Host Interactions.Journal of clinical & cellular immunology · 2015Article
- Swine interferon-induced transmembrane protein, sIFITM3, inhibits foot-and-mouth disease virus infection in vitro and in vivo.Antiviral research · 2014Article
- Foot-and-mouth disease virus 3C protease cleaves NEMO to impair innate immune signaling.Journal of virology · 2012Article
- Cattle remain immunocompetent during the acute phase of foot-and-mouth disease virus infection.Veterinary research · 2011Article
- RNA structural domains in noncoding regions of the foot-and-mouth disease virus genome trigger innate immunity in porcine cells and mice.Journal of virology · 2011Article
- Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced RANTES transcription in PK-15 cells.Virus genes · 2011Article
- Induction of foot-and-mouth disease virus-specific cytotoxic T cell killing by vaccination.Clinical and vaccine immunology : CVI · 2011Article
- Dendritic Cells and HIV-1 Trans-Infection.Viruses · 2010Article
- Immunity to emerging pathogens.Immunological reviews · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryThe interface between successful pathogens and their hosts is often a tenuous balance. In acute viral infections, this balance involves induction and inhibition of innate responses. Foot-and-mouth disease virus (FMDV) is considered one of the most contagious viruses known and is characterized by rapid induction of clinical disease in cloven hoofed animals exposed to infection. Viral shedding is extensive before the equally rapid resolution of acute disease. This positive strand RNA virus is an extremely successful pathogen, due in part to the ability to interrupt the innate immune response. Previous reviews have described the inhibition of cellular innate responses in the infected cell both in vitro and in vivo. Here, we present a review of virus inhibition of cells that are a source of antiviral function in swine. Particularly in the case of dendritic cells and natural killer cells, the virus has evolved mechanisms to interrupt the normal function of these important mediators of innate function, even though these cells are not infected by the virus. Understanding how this virus subverts the innate response will provide valuable information for the development of rapidly acting biotherapeutics to use in response to an outbreak of FMDV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.