Evidence map›Paper›PMID 18836333›Full record

ArticleCancer journal (Sudbury, Mass.)

Contemporary epidemiology of renal cell cancer.

Wong-Ho Chow, Susan S Devesa

Abstract read
In one paragraph

Article in Cancer journal (Sudbury, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 7 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 7 syntheses or guidelines pooled it, 282 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. SEOM clinical guidelines for the treatment of renal cell carcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2014
    Guideline
  8. Trial
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  11. Review
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  18. Review
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  20. The Impact of COVID-19 on New Kidney Cancer Diagnosis: Stage and Treatment in Northern Italy.International journal of environmental research and public health · 2023
    Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Wong-Ho ChowDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892-7240, USA. choww@mail.nih.gov
Susan S Devesa
Division of Cancer Epidemiology and GeneticsNational Institutes of Health · US

Funding

Cancer Risk in Human PopulationsZIACP010136 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PURDUE, MARK · 2009 to 2025
$36.7M
CANCER RISK IN HUMAN POPULATIONSZ01CP010136 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SILVERMAN, DEBRA · 1997 to 2008
$5.1M
Intramural NIH HHS Z01 CP010136
6 · The paper itself

Abstract

We analyzed renal cell cancer incidence patterns in the United States and reviewed recent epidemiologic evidence with regard to environmental and host genetic determinants of renal cell cancer risk. Renal cell cancer incidence rates continued to rise among all racial/ethnic groups in the United States, across all age groups, and for all tumor sizes, with the most rapid increases for localized stage disease and small tumors. Recent cohort studies confirmed the association of smoking, excess body weight, and hypertension with an elevated risk of renal cell cancer, and suggested that these factors can be modified to reduce the risk. There is increasing evidence for an inverse association between renal cell cancer risk and physical activity and moderate intake of alcohol. Occupational exposure to trichloroethylene has been positively associated with renal cell cancer risk in several recent studies, but its link with somatic mutations of the von Hippel-Lindau gene has not been confirmed. Studies of genetic polymorphisms in relation to renal cell cancer risk have produced mixed results, but genome-wide association studies with larger sample size and a more comprehensive approach are underway. Few epidemiologic studies have evaluated risk factors by subtypes of renal cell cancer defined by somatic mutations and other tumor markers.

Indexed as

Age DistributionAntihypertensive AgentsBiomarkers, TumorCarcinoma, Renal CellDietEnvironmentFemaleGenetic Predisposition to DiseaseGonadal Steroid HormonesHumansHypertensionIncidenceKidney NeoplasmsMotor ActivityObesityOccupationsAntihypertensive AgentsBiomarkers, TumorGonadal Steroid Hormones

Identifiers

PMID18836333
PMCPMC3077538
OpenAlexW2051762635

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.