ArticleJournal of experimental botany2008
An autophagy-associated Atg8 protein is involved in the responses of Arabidopsis seedlings to hormonal controls and abiotic stresses.
Article in Journal of experimental botany, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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Who cites it
67 citing papers in PubMed.
- Sulfite dynamics affect drought tolerance and water status in Arabidopsis and tomato.Journal of experimental botany · 2026Article
- Selective autophagy receptor VISP1 enhances cytokinin signaling by modulating the Type-A/B ARR feedback loop during root development.Science advances · 2026Article
- Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development.Frontiers in plant science · 2026Review
- Identification of the ZmATG18 subfamily genes in maize and the role of ZmATG18a in drought stress.BMC genomics · 2025Article
- Review
- SlMDH3 Interacts with Autophagy Receptor Protein SlATI1 and Positively Regulates Tomato Heat Tolerance.International journal of molecular sciences · 2024Article
- The Phytophthora parasitica effector AVH195 interacts with ATG8, attenuates host autophagy, and promotes biotrophic infection.BMC biology · 2024Article
- Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change.Scientifica · 2024Review
- Functional specialization of chloroplast vesiculation (Frontiers in plant science · 2023Article
- Autophagy and Programmed Cell Death Are Critical Pathways in Jasmonic Acid Mediated Saline Stress Tolerance in Oryza sativa.Applied biochemistry and biotechnology · 2022Article
- Genome-Wide Identification and Functional Characterization Reveals the Pivotal Roles ofInternational journal of molecular sciences · 2022Article
- Review
- Overexpression ofInternational journal of molecular sciences · 2022Article
- Article
- Histidine kinase inhibitors impair shoot regeneration inFrontiers in plant science · 2022Article
- An Overview of the Molecular Mechanisms and Functions of Autophagic Pathways in Plants.Plant signaling & behavior · 2021Article
- Autophagy in Plant Abiotic Stress Management.International journal of molecular sciences · 2021Review
- Plant Autophagy: An Intricate Process Controlled by Various Signaling Pathways.Frontiers in plant science · 2021Review
- Signaling Responses to N Starvation: Focusing on Wheat and Filling the Putative Gaps With Findings Obtained in Other Plants. A Review.Frontiers in plant science · 2021Review
- Autophagy mediates grain yield and nitrogen stress resistance by modulating nitrogen remobilization in rice.PloS one · 2021Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eukaryotes contain a ubiquitous family of autophagy-associated Atg8 proteins. In animal cells, these proteins have multiple functions associated with growth, cancer, and degenerative diseases, but their functions in plants are still largely unknown. To search for novel functions of Atg8 in plants, the present report tested the effect of expression of a recombinant AtAtg8 protein, fused at its N-terminus to green fluorescent protein (GFP) and at its C-terminus to the haemagglutinin epitope tag, on the response of Arabidopsis thaliana plants to the hormones cytokinin and auxin as well as to salt and osmotic stresses. Expression of this AtAtg8 fusion protein modulates the effect of cytokinin on root architecture. Moreover, expression of this fusion protein also reduces shoot anthocyanin accumulation in response to cytokinin feeding to the roots, implying the participation of AtAtg8 in cytokinin-regulated root-shoot communication. External application of cytokinin leads to the formation of novel GFP-AtAtg8-containing structures in cells located in the vicinity of the root vascular system, which are clearly distinct in size and dynamic movement from the GFP-AtAtg8-containing autophagosome-resembling structures that were observed in root epidermis cells. Expression of the AtAtg8 fusion construct also renders the plants more sensitive to a mild salt stress and to a lesser extent to a mild osmotic stress. This sensitivity is also associated with various changes in the root architecture, which are morphologically distinct from those observed in response to cytokinin. The results imply multiple functions for AtAtg8 in different root tissues that may also be regulated by different mechanisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.