ArticleBiophysical journal2009
Membrane-protein interactions in a generic coarse-grained model for lipid bilayers.
Article in Biophysical journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- The Evolution of Lipids from Solvents to Substrates.Annual review of biophysics · 2026Review
- Nanoporous Membranes of Densely Packed Carbon Nanotubes Formed by Lipid-Mediated Self-Assembly.ACS applied bio materials · 2024Review
- Influence of sugar concentration on the vesicle compactness, deformation and membrane poration induced by anionic nanoparticles.PloS one · 2022Article
- Membrane-Mediated Interactions Between Protein Inclusions.Frontiers in molecular biosciences · 2021Review
- Lattice Models for Protein Organization throughout Thylakoid Membrane Stacks.Biophysical journal · 2020Article
- Coupling of Membrane Nanodomain Formation and Enhanced Electroporation near Phase Transition.Biophysical journal · 2019Article
- Directed Supramolecular Organization of N-BAR Proteins through Regulation of H0 Membrane Immersion Depth.Scientific reports · 2018Article
- Curvature correction to the mobility of fluid membrane inclusions.The European physical journal. E, Soft matter · 2016Article
- Architecture and Function of Mechanosensitive Membrane Protein Lattices.Scientific reports · 2016Article
- The role of membrane-mediated interactions in the assembly and architecture of chemoreceptor lattices.PLoS computational biology · 2014Article
- More than the sum of its parts: coarse-grained peptide-lipid interactions from a simple cross-parametrization.The Journal of chemical physics · 2014Article
- Poisson's Ratio and Young's Modulus of Lipid Bilayers in Different Phases.Frontiers in bioengineering and biotechnology · 2014Article
- The role of shape complementarity in the protein-protein interactions.Scientific reports · 2013Article
- Limited perturbation of a DPPC bilayer by fluorescent lipid probes: a molecular dynamics study.The journal of physical chemistry. B · 2013Article
- Monolayer curvature stabilizes nanoscale raft domains in mixed lipid bilayers.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Directional interactions and cooperativity between mechanosensitive membrane proteins.Europhysics letters · 2013Article
- Effect of capsid confinement on the chromatin organization of the SV40 minichromosome.Nucleic acids research · 2013Article
- Coarse-grained computer simulation of dynamics in thylakoid membranes: methods and opportunities.Frontiers in plant science · 2013Review
- A generic force field for protein coarse-grained molecular dynamics simulation.International journal of molecular sciences · 2012Article
- Hierarchical Order Parameters for Macromolecular Assembly Simulations I: Construction and Dynamical Properties of Order Parameters.Journal of chemical theory and computation · 2012Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We study membrane-protein interactions and membrane-mediated protein-protein interactions by Monte Carlo simulations of a generic coarse-grained model for lipid bilayers with cylindrical hydrophobic inclusions. The strength of the hydrophobic force and the hydrophobic thickness of the proteins are systematically varied. The results are compared with analytical predictions of two popular analytical theories: The Landau-de Gennes theory and the elastic theory. The elastic theory provides an excellent description of the fluctuation spectra of pure membranes and successfully reproduces the deformation profiles of membranes around single proteins. However, its prediction for the potential of mean force between proteins is not compatible with the simulation data for large distances. The simulations show that the lipid-mediated interactions are governed by five competing factors: direct interactions; lipid-induced depletion interactions; lipid bridging; lipid packing; and a smooth long-range contribution. The mechanisms leading to hydrophobic mismatch interactions are critically analyzed.
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