Evidence map›Paper›PMID 18834500›Full record

ArticleGenome biology2008

Concept recognition for extracting protein interaction relations from biomedical text.

William A Baumgartner, Zhiyong Lu, Helen L Johnson, J Gregory Caporaso, Jesse Paquette, Anna Lindemann, Elizabeth K White, Olga Medvedeva, K Bretonnel Cohen, Lawrence Hunter

Abstract read
In one paragraph

Article in Genome biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  7. BC4GO: a full-text corpus for the BioCreative IV GO task.Database : the journal of biological databases and curation · 2014
    Article
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  9. Assessment of software testing and quality assurance in natural language processing applications and a linguistically inspired approach to improving it.Trustworthy eternal systems via evolving software, data and knowledge : second international workshop, EternalS 2012, Montpellier, France, August 28, 2012, revised selected papers. EternalS (Workshop) (2nd : 2012 : Montpellier, France) · 2013
    Article
  10. Article
  11. Article
  12. Parenthetically speaking: classifying the contents of parentheses for text mining.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2011
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. SimConcept: A Hybrid Approach for Simplifying Composite Named Entities in Biomedicine.ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

William A BaumgartnerCenter for Computational Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.
Zhiyong Lu
Helen L Johnson
J Gregory Caporaso
Jesse Paquette
Anna Lindemann
Elizabeth K White
Olga Medvedeva
K Bretonnel Cohen
Lawrence Hunter

Funding

Technology Development for a MolBio Knowledge-BaseR01LM008111 · NLM · UNIVERSITY OF COLORADO DENVER · PI HUNTER, LAWRENCE E · 2004 to 2021
$9.7M
Bio Text NLPR01LM009254 · NLM · UNIVERSITY OF COLORADO DENVER · PI HUNTER, LAWRENCE E · 2006 to 2018
$5.9M
NLM NIH HHS R01 LM008111NLM NIH HHS R01-LM008111NLM NIH HHS R01 LM009254NLM NIH HHS R01-LM009254
6 · The paper itself

Abstract

backgroundReliable information extraction applications have been a long sought goal of the biomedical text mining community, a goal that if reached would provide valuable tools to benchside biologists in their increasingly difficult task of assimilating the knowledge contained in the biomedical literature. We present an integrated approach to concept recognition in biomedical text. Concept recognition provides key information that has been largely missing from previous biomedical information extraction efforts, namely direct links to well defined knowledge resources that explicitly cement the concept's semantics. The BioCreative II tasks discussed in this special issue have provided a unique opportunity to demonstrate the effectiveness of concept recognition in the field of biomedical language processing.

resultsThrough the modular construction of a protein interaction relation extraction system, we present several use cases of concept recognition in biomedical text, and relate these use cases to potential uses by the benchside biologist.

conclusionCurrent information extraction technologies are approaching performance standards at which concept recognition can begin to deliver high quality data to the benchside biologist. Our system is available as part of the BioCreative Meta-Server project and on the internet http://bionlp.sourceforge.net.

Indexed as

Biomedical ResearchDatabases, BibliographicInformation Storage and RetrievalPattern Recognition, AutomatedProtein Interaction MappingGenes

Identifiers

PMID18834500
PMCPMC2559993

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.