Evidence map›Paper›PMID 18834320›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2008

Differences in clinical presentation among persons with pulmonary tuberculosis: a comparison of documented and undocumented foreign-born versus US-born persons.

Jacqueline M Achkar, Tsering Sherpa, Hillel W Cohen, Robert S Holzman

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Border Lookout: Enhancing Tuberculosis Control on the United States-Mexico Border.The American journal of tropical medicine and hygiene · 2015
    Article
  9. Review
  10. Article
  11. Independent association of younger age with hemoptysis in adults with pulmonary tuberculosis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2012
    Article
  12. Article
  13. Article
  14. Review
  15. Article
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  17. Ethical considerations about reporting research results with potential for further stigmatization of undocumented immigrants.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2009
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jacqueline M AchkarDepartment of Medicine and Epidemiology, Albert Einstein College of Medicine, Bronx, New York 10461, USA. jachkar@aecom.yu.edu
Tsering Sherpa
Hillel W Cohen
Robert S Holzman
New York University · USAlbert Einstein College of Medicine · US

Funding

NIAID AIDS INSTITUTIONAL TRAINING GRANTT32AI007382 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BORKOWSKY, WILLIAM · 1990 to 2004
$1.1M
Immunodiagnostic Tests for the Rapid Diagnosis of TbK23AI067665 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI ACHKAR, JACQUELINE MICHELE · 2007 to 2011
$666k
NIAID NIH HHS K23 AI067665NIAID NIH HHS T32 AI007382NIAID NIH HHS T32 AI07382
6 · The paper itself

Abstract

backgroundMost cases of tuberculosis (TB) in the United States are diagnosed in foreign-born persons, and undocumented foreign-born persons may face particular barriers to timely access to health care services. This study investigates whether differences in clinical presentations among persons with pulmonary TB are associated with foreign birth or documentation status.

methodsIn this cross-sectional study, we reviewed the medical records of patients who had received a diagnosis of microbiologically proven pulmonary TB at a New York City public hospital during the period April 1999 through March 2005. Three groups of patients with pulmonary TB (US-born persons, foreign-born persons with documents, and undocumented, foreign-born persons) were defined and compared at presentation. Odds ratios (ORs) for a symptom duration >or=8 weeks before hospital admission for each group were estimated using logistic regression.

resultsAmong 194 subjects with newly diagnosed pulmonary TB, 61 (31%) were US born, 62 (32%) were documented foreign-born persons, and 71 (37%) were undocumented foreign-born persons. Undocumented foreign-born persons presented with significantly higher frequencies of cough (P = .020) and hemoptysis P = .012 and had a significantly longer median duration of symptoms, compared with US-born persons (8 vs. 4 weeks; P = .023). No statistically significant differences between documented foreign-born and US-born persons were observed. Multivariate analysis revealed that undocumented status (compared with being US born; adjusted OR, 4.1; 95% confidence interval, 1.7-10.2; P = .0002) and being unemployed (adjusted OR, 2.2; 95% CI, 1.1-4.5; P = .023) were independently associated with a prolonged symptom duration (i.e., >or=8 weeks).

conclusionsUndocumented status was associated with an increased frequency of cough and hemoptysis and a longer duration of symptoms before medical evaluation for pulmonary TB. Whether reducing barriers to health services for undocumented foreign-born persons could enhance TB control deserves additional study.

Indexed as

AdolescentAdultAgedAged, 80 and overCross-Sectional StudiesEmigrants and ImmigrantsFemaleHumansMaleMiddle AgedMultivariate AnalysisNew York CityTime FactorsTuberculosis, Pulmonary

Identifiers

PMID18834320
PMCPMC2746906
OpenAlexW2007619256

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.