ReviewAnnual review of pharmacology and toxicology2009
Progress in genetic studies of pain and analgesia.
Review in Annual review of pharmacology and toxicology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 169 citations in OpenAlex.
- Genetic contribution of catechol-O-methyltransferase variants in treatment outcome of low back pain: a prospective genetic association study.BMC musculoskeletal disorders · 2012Trial
- Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene.PloS one · 2011Trial
- Drug response profiles to experimental pain are opioid and pain modality specific.The journal of pain · 2011Trial
- Trial
- Pharmacogenetic Approach to Tramadol Use in the Arab Population.International journal of molecular sciences · 2024Article
- Article
- Evaluation of force pain thresholds to ensure collision safety in worker-robot collaborative operations.Frontiers in robotics and AI · 2024Article
- Future Treatment of Neuropathic Pain in Spinal Cord Injury: The Challenges of Nanomedicine, Supplements or Opportunities?Biomedicines · 2022Article
- The effect of common variants in GDF5 gene on the susceptibility to chronic postsurgical pain.Journal of orthopaedic surgery and research · 2021Article
- Pain threshold, anxiety and other factors affect intensity of postoperative pain in gastric cancer patients: A prospective cohort study.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2021Article
- Impact of Dose, Sex, and Strain on Oxaliplatin-Induced Peripheral Neuropathy in Mice.Frontiers in pain research (Lausanne, Switzerland) · 2021Article
- Genetics of pain: From rare Mendelian disorders to genetic predisposition to pain.Acta bio-medica : Atenei Parmensis · 2020Review
- C57BL/6 substrain differences in formalin-induced pain-like behavioral responses.Behavioural brain research · 2020Article
- The pain trajectory of juvenile idiopathic arthritis (JIA): translating from adolescent patient report to behavioural sensitivity in a juvenile animal model.Pediatric rheumatology online journal · 2019Article
- The analgesic efficacy of morphine varies with rat strain and experimental pain model: implications for target validation efforts in pain drug discovery.European journal of pain (London, England) · 2019Article
- Article
- Genetic study in patients operated dentally and anesthetized with articaine-epinephrine.Journal of pain research · 2019Article
- Towards a neurobiological understanding of pain in chronic pancreatitis: mechanisms and implications for treatment.Pain reports · 2017Review
- Inflammatory 'double hit' model of temporomandibular joint disorder with elevated CCL2, CXCL9, CXCL10, RANTES and behavioural hypersensitivity in TNFR1/R2-/- mice.European journal of pain (London, England) · 2017Article
- Dexamethasone-suppressed Salivary Cortisol and Pain Sensitivity in Female Twins.The Clinical journal of pain · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Interindividual variability in pain sensitivity and the response to analgesic manipulations remains a considerable clinical challenge as well as an area of intense scientific investigation. Techniques in this field have matured rapidly so that much relevant data have emerged only in the past few years. Our increasing understanding of the genetic mediation of these biological phenomena have nonetheless revealed their surprising complexity. This review provides a comprehensive picture and critical analysis of the field and its prospects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.