ArticleMolecular biology and evolution2008
Different selective pressures shape the molecular evolution of color vision in chimpanzee and human populations.
Article in Molecular biology and evolution, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
- Article
- Photopigment genes, cones, and color update: disrupting the splicing code causes a diverse array of vision disorders.Current opinion in behavioral sciences · 2019Article
- Article
- Color Vision Variation as Evidenced by Hybrid L/M Opsin Genes in Wild Populations of TrichromaticInternational journal of primatology · 2014Article
- The molecular evolutionary dynamics of the vomeronasal receptor (class 1) genes in primates: a gene family on the verge of a functional breakdown.Frontiers in neuroanatomy · 2014Review
- A system-level, molecular evolutionary analysis of mammalian phototransduction.BMC evolutionary biology · 2013Article
- A trans-specific polymorphism in ZC3HAV1 is maintained by long-standing balancing selection and may confer susceptibility to multiple sclerosis.Molecular biology and evolution · 2012Article
- Recent advances in understanding the role of nutrition in human genome evolution.Advances in nutrition (Bethesda, Md.) · 2011Review
- Gene conversion and purifying selection shape nucleotide variation in gibbon L/M opsin genes.BMC evolutionary biology · 2011Article
- Comparative analysis of evolutionary dynamics of genes encoding leucine-rich repeat receptor-like kinase between rice and Arabidopsis.Genetica · 2011Article
- Article
- Genomic-scale capture and sequencing of endogenous DNA from feces.Molecular ecology · 2010Article
- Evolutionary adaptations to dietary changes.Annual review of nutrition · 2010Review
- Haplotype structure and divergence at human and chimpanzee serotonin transporter and receptor genes: implications for behavioral disorder association analyses.Molecular biology and evolution · 2010Article
- Color vision diversity and significance in primates inferred from genetic and field studies.Genes & genomicsReview
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
A population genetic analysis of the long-wavelength opsin (OPN1LW, "red") color vision gene in a global sample of 236 human nucleotide sequences had previously discovered nine amino acid replacement single nucleotide polymorphisms, which were found at high frequencies in both African and non-African populations and associated with an unusual haplotype diversity. Although this pattern of nucleotide diversity is consistent with balancing selection, it has been argued that a recombination "hot spot" or gene conversion within and between X-linked color vision genes alone may explain these patterns. The current analysis investigates a closely related primate with trichromatism to determine whether color vision gene amino acid polymorphism and signatures of adaptive evolution are characteristic of humans alone. Our population sample of 56 chimpanzee (Pan troglodytes) OPN1LW sequences shows three singleton amino acid polymorphisms and no unusual recombination or linkage disequilibrium patterns across the approximately 5.5-kb region analyzed. Our comparative population genetic approach shows that the patterns of OPN1LW variation in humans and chimpanzees are consistent with positive and purifying selection within the two lineages, respectively. Although the complex role of color vision has been greatly documented in primate evolution in general, it is surprising that trichromatism has followed very different selective trajectories even between humans and our closest relatives.
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