ArticleInternational journal of clinical and experimental pathology2009
Infection and cervical neoplasia: facts and fiction.
Article in International journal of clinical and experimental pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Association between HLA-DP Gene Polymorphisms and Cervical Cancer Risk: A Meta-Analysis.BioMed research international · 2018Pooled it
- Herpes simplex virus type 2 in sub-Saharan Africa and the potential impact of helminth immune modulation.Frontiers in cellular and infection microbiology · 2024Review
- Human Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review.Pathogens (Basel, Switzerland) · 2020Review
- Cervical Cancer, Different Treatments and Importance of Bile Acids as Therapeutic Agents in This Disease.Frontiers in pharmacology · 2019Review
- Human Leukocyte Antigen (HLA) Class II -DRB1 and -DQB1 Alleles and the Association with Cervical Cancer in HIV/HPV Co-Infected Women in South Africa.Journal of Cancer · 2019Article
- The interaction between human papillomavirus and other viruses.Virus research · 2017Review
- Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review.Journal of immunology research · 2017Review
- Association of human papillomavirus and Chlamydia trachomatis with intraepithelial alterations in cervix samples.Memorias do Instituto Oswaldo Cruz · 2016Article
- Association between human papillomavirus and Epstein - Barr virus DNA and gene promoter methylation of RB1 and CDH1 in the cervical lesions: a transversal study.Diagnostic pathology · 2015Article
- Autophagy knocked down by high-risk HPV infection and uterine cervical carcinogenesis.International journal of clinical and experimental medicine · 2015Review
- Seminal plasma induces the expression of IL-1α in normal and neoplastic cervical cells via EP2/EGFR/PI3K/AKT pathway.Journal of molecular signaling · 2014Article
- Article
- Epigenetic mechanisms in penile carcinoma.International journal of molecular sciences · 2013Review
- High prevalence and genotypic diversity of the human papillomavirus in Amazonian women, Brazil.Infectious diseases in obstetrics and gynecology · 2013Article
- Modeling the impact of the difference in cross-protection data between a human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine and a human papillomavirus (HPV)-6/11/16/18 vaccine in Canada.BMC public health · 2012Article
- Correlation between ebv co-infection and HPV16 genome integrity in Tunisian cervical cancer patients.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2012Article
- Seminal plasma enhances cervical adenocarcinoma cell proliferation and tumour growth in vivo.PloS one · 2012Article
- Cervical cancer prevention in low- and middle-income countries: feasible, affordable, essential.Cancer prevention research (Philadelphia, Pa.) · 2012Review
- Role of bacteria in oncogenesis.Clinical microbiology reviews · 2010Review
- HPV vaccination in Ireland.Irish journal of medical science · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whilst there is strong evidence that human papillomavirus (HPV) is the principal aetiological agent in cervical neoplasia, some other sexually transmitted agents may either contribute or protect against cervical carcinogenesis, such as the herpes virus family (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), human immunodeficiency virus (HIV) or Chlamydia trachomatis (CT). Epidemiological studies suggest that HSV may have a role in cervical neoplasia, but there is no clear supportive experimental evidence. Serological studies have also failed to reveal a difference in the prevalence of antibodies to CMV and EBV between patients with cervical cancer and controls. However, longitudinal seroepidemiological studies have provided evidence that CT is an independent risk factor for the development of cervical squamous carcinoma and this association is serotype specific. The increased risk of cervical neoplasia in patients infected with HIV has been recognised for over a decade and HIV may interact with HPV either by alternating HPV gene transcription or by immunosuppression. Finally extensive experimental and limited epidemiological evidence suggests that adeno-associated viruses (AAV) may have antioncogenic activity in man and may protect against the development of cervical cancer. At present the mechanism of this action is unclear but may relate to AAV-induced regulation of HPV gene expression and the HPV life cycle. In this review we summarize the current literature relating to the associations and mechanisms of cervical carcinogenesis by each of these infectious microorganisms.
Indexed as
Identifiers
18830380PMC2491386W13658042What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.